PMID: 9523803Apr 2, 1998Paper

Transient neurologic symptoms after spinal anesthesia with mepivacaine and lidocaine

Anesthesiology
G A LiguoriM F Chisholm

Abstract

Spinal anesthesia with lidocaine is ideal for ambulatory surgery because of its short duration of action. However, transient neurologic symptoms (TNS) occur in 0-40% of patients. The incidence of TNS with mepivacaine, which has a similar duration of action, is unknown. Sixty ambulatory patients undergoing knee arthroscopy received spinal anesthesia in a randomized, double-blinded manner, with either 45 mg 1.5% mepivacaine or 60 mg 2% lidocaine. An L3-L4 midline approach was used with a 27-gauge Whitacre needle and a 20-gauge introducer. The local anesthetic was injected over approximately 30 s with the aperture of the Whitacre needle in a cephalad direction. Two to 4 days after operation, each patient was questioned about the development of TNS. In addition, the two groups were compared for time to regression of sensory and motor blockade and time to discharge milestones. Three patients receiving lidocaine were lost to follow-up. None of the 30 patients in the mepivacaine group developed TNS, whereas 6 of 27 (22%) in the lidocaine group did (P = 0.008). Time to regression to the L5 sensory level and to complete resolution of motor block were similar in both groups. The times to discharge milestones were also comparable. The inc...Continue Reading

References

Mar 1, 1991·Anesthesia and Analgesia·M L RiglerD Bohner
Jul 1, 1967·Anesthesia and Analgesia·E O HenschelJ J Jacoby
Oct 1, 1966·American Journal of Obstetrics and Gynecology·E LiptonB Batt
Mar 1, 1966·Anesthesia and Analgesia·E S SikerM T Pappas
Jan 1, 1966·Acta Anaesthesiologica Scandinavica. Supplementum·A M el-ShirbinyM Motaweh
Dec 1, 1995·Anesthesia and Analgesia·K F HamplJ Drewe
Mar 1, 1995·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·G R PinczowerM Lowmiller
May 1, 1993·Anesthesia and Analgesia·M SchneiderA von Hochstetter
Oct 1, 1996·Anesthesia and Analgesia·B Ben-DavidS Vaida
Nov 1, 1956·British Journal of Anaesthesia·K G DHUNERL R ULFENDAHL

❮ Previous
Next ❯

Citations

Oct 27, 2009·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Dermot O'DonnellRichard Brull
Aug 10, 2000·Anesthesiology Clinics of North America·P S Hodgson, S S Liu
Mar 14, 2001·Anesthesiology Clinics of North America·J A Murdoch, T J Gan
Nov 25, 2000·Journal of Clinical Anesthesia·R R Gaiser
Oct 8, 2003·Best Practice & Research. Clinical Anaesthesiology·William F Urmey
Feb 24, 2001·Acta Anaesthesiologica Scandinavica·A LindhL Westman
Jun 2, 2000·Regional Anesthesia and Pain Medicine·P S HodgsonJ M Neal
May 23, 2002·Regional Anesthesia and Pain Medicine·Suzanne L HuffnagleValerie A Arkoosh
Nov 14, 2002·Regional Anesthesia and Pain Medicine·Julia E Pollock
Jun 23, 2005·International Anesthesiology Clinics·Richard L Kahn, David A Nelson
Jul 10, 2009·Regional Anesthesia and Pain Medicine·Tamie TakenamiSumio Hoka
Feb 13, 2001·Anesthesia and Analgesia·M C Schneider, D J Birnbach
Jun 24, 2003·Anesthesia and Analgesia·Toshiharu KasabaMayumi Takasaki
Aug 24, 2005·Anesthesia and Analgesia·Jacques T YaDeauVictor M Zayas
Nov 24, 2004·Drugs & Aging·Ban C H TsuiBrendan Finucane
Apr 12, 2005·Drugs·Chester C Buckenmaier, Lisa L Bleckner
May 16, 2014·Current Opinion in Anaesthesiology·Hillenn Cruz EngKi Jinn Chin
Sep 18, 1999·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·L BergeronC Boucher
Oct 8, 2003·Best Practice & Research. Clinical Anaesthesiology·Julia E Pollock
Oct 4, 2006·Current Opinion in Anaesthesiology·T Standl, M A Burmeister
Oct 4, 2006·Current Opinion in Anaesthesiology·K F HamplK Drasner
Oct 7, 2006·Current Opinion in Anaesthesiology·José L Aguilar, R Peláez
Nov 7, 1999·Anesthesiology·P E GautierJ L Hody
Jun 5, 2001·Anesthesiology·S S Liu, S B McDonald
Sep 20, 2000·Mayo Clinic Proceedings·M E Johnson
Oct 31, 2007·Current Medical Research and Opinion·Dorothee H BremerichChristian Byhahn
Sep 17, 2004·Regional Anesthesia and Pain Medicine·Tamie TakenamiSumio Hoka
Dec 21, 2002·Best Practice & Research. Clinical Anaesthesiology·Francis V Salinas, Spencer S Liu
Dec 11, 2014·Regional Anesthesia and Pain Medicine·Tamie TakenamiTadashi Kawakami
Jun 19, 2003·Anesthesiology Clinics of North America·Brid McGrath, Frances Chung

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.