Transient pressure signals in mechanical heart valve cavitation

ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs
Z J WuN H Hwang

Abstract

The purpose of this investigation was to establish a correlation between mechanical heart valve (MHV) cavitation and transient pressure (TP) signals at MHV closure. This correlation may suggest a possible method to detect in vivo MHV cavitation. In a pulsatile mock flow loop, a study was performed to measure TP and observe cavitation bubble inception at MHV closure under simulated physiologic ventricular and aortic pressures at heart rates of 70, 90, 120, and 140 beats/min with corresponding cardiac outputs of 5.0, 6.0, 7.5, and 8.5 L/min, respectively. The experimental study included two bileaflet MHV prostheses: 1) St. Jude Medical 31 mm and 2) Carbomedics 31 mm. High fidelity piezo-electric pressure transducers were used to measure TP immediately before and after the valve leaflet/housing impact. A stroboscopic lighting imaging technique was developed to capture cavitation bubbles on the MHV inflow surfaces at selected time delays ranging from 25 microseconds to 1 ms after the leaflet/housing impact. The TP traces measured 10 mm away from the valve leaflet tip showed a large pressure reduction peak at the leaflet/housing impact, and subsequent high frequency pressure oscillations (HPOs) while the cavitation bubbles were obse...Continue Reading

Citations

Aug 5, 2005·Annals of Biomedical Engineering·Changfu WuNed H C Hwang
May 22, 2010·Annals of Biomedical Engineering·Chi-Wen LoPo-Chien Lu
Nov 19, 2003·Journal of Biomechanical Engineering·Peter JohansenHans Nygaard
Jan 22, 2008·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Hwansung LeeYoshiyuki Taenaka
Mar 22, 2008·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Chi-Wen LoNed H Hwang
Jun 3, 2004·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Koki TakiuraKou Imachi
Nov 25, 2004·The International Journal of Artificial Organs·M J Eichler, H M Reul

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