PMID: 1200727Dec 1, 1975Paper

Transient red blood cell aplasia in association with viral hepatitis. Occurrence four years apart in siblings

Archives of Internal Medicine
D A SearsM S Gold

Abstract

Transient pure red blood cell aplasia was verified during the course of viral hepatitis in two siblings whose illnesses occurred four years apart. The duration and course of the anemia was very similar in the two subjects, and in both the hepatitis progressed to a chronic active form. Autoimmune phenomena were prominent in one patient and suggested in the other, but a cytotoxic antibody to erythroblasts could not be demonstrated in the one patient in whom it was sought. The unique occurrence of such a syndrome in siblings, widely separated in time, suggests the possibility of a genetic predisposition governing the unusual response to a common illness.

Citations

Jan 1, 1983·The American Journal of Medicine·J B ZeldisR P Gale
Jan 1, 1993·Journal of Internal Medicine·G J CreemersC van der Heul
Aug 1, 1980·Journal of Clinical Pathology·J H RobertsonD C Salmon
Aug 1, 1996·Journal of Gastroenterology·S TomidaT Abe
Jan 1, 1989·Scandinavian Journal of Infectious Diseases·S G GundersenJ N Bruun

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.