PMID: 9161052May 1, 1997Paper

Transient suppression of macrophage functions by liposome-encapsulated drugs

Trends in Biotechnology
Nico van RooijenA Sanders

Abstract

Macrophages play an important role in host defense reactions, for example, by phagocytosis of particulate materials. This process also results in the rapid removal of targeting devices such as liposomes and adenovirus vectors and of non-autologous grafted cells and materials. Another aspect of macrophage function is their production and secretion of proinflammatory cytokines. Transient and organ-specific suppression of macrophage function by liposome-mediated manipulation has been shown to improve the efficacy of drug and gene targeting and to reduce the symptoms of inflammatory reactions.

References

Jul 1, 1992·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·C A Toth, P Thomas
Mar 1, 1990·Journal of Leukocyte Biology·F G DelemarreN van Rooijen
Oct 1, 1990·The Journal of Experimental Medicine·I HuitingaC D Dijkstra
Nov 1, 1995·Immunology Today·M Tary-LehmannP V Lehmann
Jun 1, 1995·The Journal of Clinical Investigation·P B McCrayM J Welsh
Jul 1, 1995·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·K VanderkerkenE Wisse
Dec 27, 1994·European Journal of Pharmacology·Y L ChenL Chauvelot-Moachon
Jan 1, 1995·Scandinavian Journal of Rheumatology. Supplement·P L van LentW B van den Berg
May 29, 1995·International Journal of Cancer. Journal International Du Cancer·T DaemenG L Scherphof
Nov 1, 1994·Antimicrobial Agents and Chemotherapy·G F BrisseauO D Rotstein
Sep 14, 1994·Journal of Immunological Methods·N Van Rooijen, A Sanders
May 1, 1993·Infection·Y LermanY L Danon
May 1, 1993·Infection and Immunity·S G VredenM F Van Den Broek
Oct 1, 1995·Archives of Histology and Cytology·R RezzaniR G Ventura
Dec 1, 1995·Trends in Biotechnology·G Gregoriadis
Mar 1, 1996·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·F ChenL M Demers
May 1, 1996·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·N Van Rooijen, A Sanders
Mar 1, 1996·The American Journal of Physiology·L VacaL D Possani
Jun 14, 1996·Journal of Immunological Methods·N van RooijenT K van den Berg

❮ Previous
Next ❯

Citations

Mar 20, 2002·Veterinary Microbiology·Aouatef DjerabaPascale Quéré
Dec 21, 2000·Immunology·J Zhang-HooverJ Stein-Streilein
Sep 27, 2003·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Gabriele SassGisa Tiegs
Jan 20, 1999·The Journal of Experimental Medicine·H S JunJ W Yoon
Sep 10, 2008·The Journal of Experimental Medicine·Daniel R GettsNicholas J C King
Feb 3, 2005·Human Gene Therapy·Daniel A Muruve
Jul 28, 2011·The Journal of Infectious Diseases·Isao MiyairiGerald I Byrne
Jun 18, 2004·Transplantation·Tanja P A M SlegersRuth van der Gaag
Sep 3, 2005·The Journal of Clinical Investigation·Kazuichi MaruyamaJ Wayne Streilein
Aug 4, 2006·The Journal of Clinical Investigation·Athanasios StratisIngo Haase
Sep 19, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Kevin P HornJerry Silver
May 7, 2014·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Qiang XiaoYu Yang
Jan 5, 2002·Journal of Neuroimmunology·Machteld M J PolflietTimo K van den Berg
Nov 13, 2008·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Yoshitsugu NukiTomoki Hashimoto
May 15, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Ekihiro SekiDavid A Brenner
Nov 9, 2005·Glia·Geneviève GowingJean-Pierre Julien
Jul 14, 2010·The British Journal of Surgery·C SchürmannS Frank
Mar 27, 2013·European Journal of Immunology·Ulrich JarryDominique Couez
Nov 14, 2000·The American Journal of Pathology·J SchümannG Tiegs
Feb 27, 2003·Journal of Liposome Research·Nico van Rooijen, Esther van Kesteren-Hendrikx
Feb 27, 2003·Journal of Liposome Research·Junichi FujimotoTeiji Sawa
Apr 14, 2016·Journal of Controlled Release : Official Journal of the Controlled Release Society·Nicolas DarvilleGuy Van den Mooter
Apr 13, 2005·Journal of Drug Targeting·Luigia RossiMauro Magnani
Jun 11, 2014·The International Journal of Biochemistry & Cell Biology·Xiaocang CaoQiang Liu
Jun 25, 2008·International Reviews of Immunology·Inderpreet SurRune Toftgård
Feb 26, 2004·Neuron·José Luis Marín-TevaMichel Mallat
Dec 3, 2014·The International Journal of Biochemistry & Cell Biology·Mei WangYongjun Li
Feb 22, 2001·The Journal of Surgical Research·Y NakamuraT Kakiuchi
Feb 27, 2013·Anesthesiology·Vincent DegosHua Su

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bioinformatics in Biomedicine

Bioinformatics in biomedicine incorporates computer science, biology, chemistry, medicine, mathematics and statistics. Discover the latest research on bioinformatics in biomedicine here.