PMID: 8613613Mar 15, 1996Paper

Transient sympathovagal imbalance triggers "ischemic" sudden death in patients undergoing electrocardiographic Holter monitoring

Journal of the American College of Cardiology
A PozzatiR Bugiardini

Abstract

The aim of this study was to investigate the relation between "ischemic" sudden death (arrhythmic death preceded by ST segment shift) and autonomic nervous system activity. Background. Mechanisms precipitating sudden death are poorly known despite the importance of detecting functional factors that may contribute to such a fatal event. We analyzed the tapes of eight patients (seven men and one woman with a mean age of 66 +/- 8 years) who had ischemic sudden death during ambulatory electrocardiographic (Holter) monitoring. Four patients had unstable and four had stable angina; none was taking antiarrhythmic drugs. Twenty patients with angina and transient myocardial ischemia during Holter monitoring served as control subjects. Arrhythmias, ST segment changes and heart rate variability were analyzed by a computerized interactive Holter system. Five patients had ventricular tachyarrhythmias (ventricular fibrillation in three, ventricular tachycardia in two), and three had bradyarrhythmias (atrioventricular block in two, sinus arrest in one) as the terminal event; all eight patients showed ST segment shift (maximal change 0.46 +/- 0.16 mV; with ST elevation in two) that occurred 41 +/- 34 min (mean +/- SD) before sudden death. The ...Continue Reading

References

Sep 1, 1991·The American Journal of Cardiology·R E KleigerJ L Fleiss
Jun 1, 1985·Journal of the American College of Cardiology·M F Oliver
Mar 1, 1982·Circulation·L E Hinkle, H T Thaler
May 1, 1993·Circulation·S N WillichJ E Muller

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Citations

Apr 23, 2013·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·A O KraaijeveldC J H J Kirchhof
Jul 20, 2010·Journal of Behavioral Medicine·Mimi R Bhattacharyya, Andrew Steptoe
Jan 5, 1999·International Journal of Cardiology·W L LeeC T Ting
Oct 20, 2004·Zeitschrift für Kardiologie·K Sroka
Dec 12, 2012·Progress in Cardiovascular Diseases·Borejda XhyheriRaffaele Bugiardini
Jul 25, 2012·Revista Portuguesa De Cardiologia : Orgão Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology·Jorge Humberto GuardadoHélder Pereira
Oct 29, 2000·The American Journal of Cardiology·F LombardiUNKNOWN Implantable Cardioverter Defibrillator-Heart Rate Variability Italian Study Group
May 12, 2004·The American Journal of Cardiology·Simon L BaconJames A Blumenthal
Aug 31, 2001·Journal of the American College of Cardiology·W J KopD S Krantz
Jun 4, 2016·Nature Reviews. Cardiology·Neha J Pagidipati, Eric D Peterson
Nov 25, 2000·The American Journal of Cardiology·T FujitaS Umemura
Aug 16, 2016·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Michał KuzemczakTomasz Siminiak
Jul 3, 2013·Nature Reviews. Cardiology·Viola VaccarinoRaffaele Bugiardini
May 13, 2009·Circulation·Shlomo Stern, Antoni Bayes de Luna
Aug 12, 2006·Journal of Occupational and Environmental Medicine·Heike Luttmann-GibsonDiane R Gold
May 20, 2008·Annals of Medicine·Martina MontagnanaGian Cesare Guidi
Jul 9, 2008·Blood Pressure·Dagmara HeringKrzysztof Narkiewicz
Dec 27, 2019·European Heart Journal·Ahmed HaiderCatherine Gebhard
May 23, 2007·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Claudia PostorinoFrancesco Romeo

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