Transition-metal-free direct anti-carboboration of alkynes with boronic acids to produce alkenylheteroarenes

Organic Letters
Silvia Roscales, Aurelio G Csákÿ

Abstract

The transition-metal-free intermolecular direct 1,2-carboboration reaction of heteroarylacetylenes using boronic acids as reagents is achieved by utilizing tartaric acid as promoter. The reaction proceeds with excellent regioselectivity and anti stereoselectivity to afford boroxole frameworks. The resulting compounds are of use for the stereoselective preparation of polysubstituted alkenylheteroarenes.

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Citations

Sep 17, 2015·Dalton Transactions : an International Journal of Inorganic Chemistry·James R LawsonMichael J Ingleson
May 4, 2018·Chemistry : a European Journal·Atsushi UenoGerhard Erker
Jun 21, 2018·Chemistry : a European Journal·Yoshiaki ShojiTakanori Fukushima

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