Transitional cell carcinoma of the ovary

Taiwanese Journal of Obstetrics & Gynecology
Chia-Hui LinEsther Shih-Chu Ho

Abstract

Transitional cell carcinoma (TCC) of the ovary is a rare, recently recognized, subtype of ovarian surface epithelial cancer. We present a case of TCC of the ovary, managed by staging operation and followed by postoperative chemotherapy with carboplatin and cyclophosphamide. A 67-year-old postmenopausal woman presented with a 2-year history of progressive enlargement of an abdominal mass. Pelvic sonography and abdominal computed tomography showed a pelvic mass measuring 210 x 165 x 203 mm. The serum CA-125 titer was also elevated (65.01 U/mL). A staging operation with total abdominal hysterectomy, bilateral salpingo-oophorectomy, infracolic omentectomy and pelvic lymph node dissection was performed. After surgery, the pathologic report of the left ovarian tumor was TCC, grade 2-3, stage IA. The patient then underwent four cycles of postoperative chemotherapy with carboplatin and cyclophosphamide. CA-125 levels declined to within the normal range after the first cycle of chemotherapy. TCC of the ovary is a rare subtype of epithelial ovarian cancer. It differs from malignant Brenner tumor by the absence of a benign or borderline Brenner component. Surgical resection is the primary therapeutic approach, and patient outcomes after c...Continue Reading

References

May 1, 1996·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·A AyhanA Ayhan

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Citations

Nov 1, 2011·Journal of the Chinese Medical Association : JCMA·Yiu-Tai LiWen-Ling Lee
Jan 28, 2014·Gynecologic Oncology·Stephanie H GusehMarcela G del Carmen
Jun 29, 2012·Oncology Letters·Satoshi IchigoAtsushi Imai

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