Transjugular intrahepatic portosystemic shunt for palliative treatment of portal hypertension secondary to portal vein tumor thrombosis

World Journal of Gastroenterology : WJG
Zai-Bo JiangShou-Hai Guan

Abstract

To evaluate the palliative therapeutic effects of transjugular intrahepatic portosystemic shunt (TIPS) in portal vein tumor thrombosis (PVTT) complicated by portal hypertension. We performed TIPS for 14 patients with PVTT due to hepatocellular carcinoma (HCC). Of the 14 patients, 8 patients had complete occlusion of the main portal vein, 6 patients had incomplete thrombosis, and 5 patients had portal vein cavernous transformation. Clinical characteristics and average survival time of 14 patients were analysed. Portal vein pressure, ascites, diarrhoea, and variceal bleeding and circumference of abdomen were assessed before and after TIPS. TIPS was successful in 10 cases, and the successful rate was about 71%. The mean portal vein pressure was reduced from 37.2 mmHg to 18.2 mmHg. After TIPS, the ascites decreased, hemorrhage stopped and the clinical symptoms disappeared in the 10 cases. The average survival time was 132.3 d. The procedure failed in 4 cases because of cavernous transformation in portal vein and severe cirrhosis. TIPS is an effective palliative treatment to control hemorrhage and ascites due to HCC complicated by PVTT.

References

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Citations

Aug 27, 2005·World Journal of Gastroenterology : WJG·Elmar SiewertSiegfried Matern
Apr 17, 2015·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Swan SpecchiGiovanna Bertolini
Aug 25, 2015·Radiology·Yong LvGuohong Han
Mar 30, 2005·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jorge A MarreroAnna S Lok
May 18, 2013·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Lei LiuGuohong Han
Mar 24, 2010·European Journal of Gastroenterology & Hepatology·Jean-Marc PerarnauJean Ayoub
Jan 19, 2021·Hepatobiliary & Pancreatic Diseases International : HBPD INT·Xiao-Yan SunChun-Qing Zhang

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