Transjugular intrahepatic portosystemic shunt versus sclerotherapy in the elective treatment of variceal hemorrhage

Gastroenterology
J CabreraD Kravetz

Abstract

Uncontrolled studies suggest that placement of a transjugular intrahepatic portosystemic shunt (TIPS) could be useful in the treatment of variceal bleeding. The aim of this study was to evaluate the efficacy and safety of TIPS in the elective treatment of hemorrhage from esophageal varices in a randomized controlled study that compared the effects of TIPS with those of endoscopic sclerotherapy (ES). Sixty-three consecutive cirrhotic patients with hemorrhage from esophageal varices were included. Thirty-two patients were randomly allocated to ES and 31 to TIPS groups. One patient in each group died before the therapeutic procedure could be performed. During a mean follow-up period of 15 months, variceal rebleeding occurred in 51.6% of the patients in the ES group and 23% of those in the TIPS group. Uncontrolled rebleeding occurred in 10 of 31 patients in the ES group, whereas rebleeding did not occur in any patient of the TIPS group. Hepatic encephalopathy was more frequent in TIPS patients (33.3%) than in those treated by ES (13%). However, mortality was similar in both treatment groups. These preliminary results suggest that TIPS is more effective than ES in the prevention of variceal rebleeding in cirrhotic patients, even tho...Continue Reading

Citations

Dec 1, 2005·Seminars in Interventional Radiology·Jorge E Lopera
Mar 15, 2000·Gut·R JalanP C Hayes
May 13, 1999·Postgraduate Medical Journal·N H PatelR M Jindal
Feb 13, 2001·Postgraduate Medical Journal·P J Gow, R W Chapman
Aug 22, 2013·World Journal of Gastroenterology : WJG·Erwin Biecker
Sep 24, 2009·The Indian Journal of Radiology & Imaging·Sundeep J Punamiya
Aug 14, 2012·International Journal of Hepatology·Gilles Pomier-LayrarguesPierre Perreault
Jan 29, 2011·Expert Opinion on Pharmacotherapy·Ulrich ThalheimerAndrew K Burroughs
Oct 14, 2011·International Journal of Hepatology·Sundeep J Punamiya, Deepak N Amarapurkar
Aug 26, 1999·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·G V PapatheodoridisA K Burroughs
Feb 3, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M W RussoR S Brown
Sep 10, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·N D GraceJ Rodes
Dec 24, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·L García-VillarrealR Fuentes
Aug 8, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M GuevaraJ Rodés
Oct 26, 1999·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·K BarangeJ P Vinel
Sep 30, 2003·Journal of Vascular and Interventional Radiology : JVIR·Ziv J HaskalUNKNOWN Society of Interventional Radiology Technology Assessment Committee
Feb 11, 2012·Clinics in Liver Disease·Oliviero RiggioManuela Merli
Feb 14, 2004·Journal of Vascular and Interventional Radiology : JVIR·Timothy W I ClarkS William Stavropoulos
Jun 28, 2011·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Harjit K Bhogal, Arun J Sanyal
Mar 2, 2016·The American Journal of Gastroenterology·Silvia NardelliOliviero Riggio
Aug 10, 2010·Critical Care Nursing Clinics of North America·James N Fleming, Ahmad Abou Abbass
Dec 29, 2009·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Oliviero RiggioStefania Angeloni
Jun 17, 2009·Techniques in Vascular and Interventional Radiology·Timothy Clark
Jun 13, 2009·Clinical Radiology·A R OwenJ G Moss
Apr 2, 2008·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·C Bureau, J P Vinel
Aug 6, 2000·Journal of Vascular and Interventional Radiology : JVIR·E M WalserR Soloway
Jan 22, 2005·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Thomas D BoyerUNKNOWN American Association for the Study of Liver Diseases
Mar 6, 2003·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Barbara Rosado, Patrick S Kamath
Aug 30, 2012·Liver International : Official Journal of the International Association for the Study of the Liver·Chris CorbettDhiraj Tripathi
Jun 1, 1997·Baillière's Clinical Gastroenterology·P S Kamath, M A McKusick
Jul 1, 1996·Annals of Vascular Surgery·W S Helton, K Johansen
Sep 22, 2001·Clinics in Liver Disease·J M Henderson
Dec 31, 2003·Gastroenterology Clinics of North America·Kevin M Comar, Arun J Sanyal

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.