Translating the Lifestyle Interventions and Independence for Elders Clinical Trial to Older Adults in a Real-World Community-Based Setting.

The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
K F ReidRoger A Fielding

Abstract

The Lifestyle Interventions and Independence for Elders (LIFE) clinical trial demonstrated that a structured program of physical activity (PA) reduced mobility-disability in older adults by up to 28%. It remains unknown whether the benefits of LIFE PA can be translated to older adults at risk for mobility-disability in real-world community-based settings. To address this knowledge gap, we conducted the ENhancing independence using Group-based community interventions for healthy AGing in Elders (ENGAGE) pilot study and examined the safety, feasibility, and preliminary effectiveness of translating LIFE PA to a community-based senior center. Forty older adults with severe lower extremity functional limitations (age: 76.9 ± 7.3 years; body mass index: 32.7 ± 8 kg/m2; 85% female; short physical performance battery score: 6.3 ± 2.2) were randomized to 24 weeks of PA or a health education control intervention. Community-based PA was safe (serious adverse events: PA vs health education, 0:2; nonserious adverse events: PA vs health education, 3:1) and participants successfully adhered to the PA intervention (65.2%). Compared to health education, PA participants who attended ≥25% of scheduled visits had meaningful and sustained short phy...Continue Reading

Associated Clinical Trials

Nov 23, 2018·Kieran Reed

References

Feb 3, 1999·International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care·R M KaplanJ P Anderson
Sep 3, 2005·Journal of the American Geriatrics Society·Sarah E LambUNKNOWN Prevention of Falls Network Europe and Outcomes Consensus Group
Sep 10, 2008·American Journal of Preventive Medicine·Sara WilcoxStacy Wegley
Jul 1, 2009·Arthritis and Rheumatism·Rachel B SeymourPankaja Desai
Jun 29, 2010·Medicine and Science in Sports and Exercise·Leena ChoiMaciej S Buchowski
Oct 26, 2010·Journal of General Internal Medicine·Susan E HardyHoward B Degenholtz
May 29, 2014·JAMA : the Journal of the American Medical Association·Marco PahorUNKNOWN LIFE study investigators
Aug 1, 2015·MMWR. Morbidity and Mortality Weekly Report·Elizabeth A Courtney-LongVincent A Campbell
Oct 19, 2017·Medicine and Science in Sports and Exercise·Amal A WanigatungaTodd M Manini

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Citations

May 30, 2019·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Heini A LiimattaKaisu H Pitkala

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