PMID: 9539745May 16, 1998Paper

Translation of cytochrome f is autoregulated through the 5' untranslated region of petA mRNA in Chlamydomonas chloroplasts

Proceedings of the National Academy of Sciences of the United States of America
Y ChoquetF A Wollman

Abstract

A process that we refer to as control by epistasy of synthesis (CES process) occurs during chloroplast protein biogenesis in Chlamydomonas reinhardtii: the synthesis of some chloroplast-encoded subunits, the CES subunits, is strongly attenuated when some other subunits from the same complex, the dominant subunits, are missing. Herein we investigate the molecular basis of the CES process for the biogenesis of the cytochrome b6f complex and show that negative autoregulation of cytochrome f translation occurs in the absence of other complex subunits. This autoregulation is mediated by an interaction, either direct or indirect, between the 5' untranslated region of petA mRNA, which encodes cytochrome f, and the C-terminal domain of the unassembled protein. This model for the regulation of cytochrome f translation explains both the decreased rate of cytochrome f synthesis in vivo in the absence of its assembly partners and its increase in synthesis when significant accumulation of the C-terminal domain of the protein is prevented. When expressed from a chimeric mRNA containing the atpA 5' untranslated region, cytochrome f no longer showed an assembly-dependent regulation of translation. Conversely, the level of antibiotic resistance...Continue Reading

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Citations

Jul 31, 2007·Photosynthesis Research·Julia Marín-NavarroStephen P Mayfield
Aug 18, 2000·Biochimie·A Barkan, M Goldschmidt-Clermont
Aug 18, 2000·Biochimie·Y Choquet, O Vallon
Apr 16, 2002·Trends in Plant Science·William Zerges
May 14, 1999·Trends in Plant Science·R K Bruick, S P Mayfield
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Mar 14, 2000·Current Opinion in Plant Biology·A R Grossman
Jan 29, 2000·The Plant Journal : for Cell and Molecular Biology·R A MondeD B Stern
Apr 12, 2000·The Plant Journal : for Cell and Molecular Biology·F E VaistijJ D Rochaix
Sep 11, 2002·The Plant Journal : for Cell and Molecular Biology·Dominique DrapierFrancis-André Wollman
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Aug 15, 2001·European Journal of Biochemistry·S PreissU Johanningmeier
Jan 24, 2013·Antioxidants & Redox Signaling·Jean-David Rochaix
Nov 20, 2002·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Elena Baena-González, Eva-Mari Aro
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May 5, 2001·Annual Review of Plant Physiology and Plant Molecular Biology·Elizabeth H Harris
Oct 25, 2012·Journal of Biomedicine & Biotechnology·Meili GaoJiangang Long
Apr 4, 2007·Proceedings of the National Academy of Sciences of the United States of America·Katia Wostrikoff, David Stern
Oct 24, 2007·Proceedings of the National Academy of Sciences of the United States of America·Raymond SurzyckiJean-David Rochaix
May 15, 2007·Proceedings of the National Academy of Sciences of the United States of America·Cécile RaynaudYves Choquet
Aug 18, 2010·Plant Molecular Biology·Francesca De MarchisMichele Bellucci
Jun 1, 2011·The Plant Journal : for Cell and Molecular Biology·Stephan EberhardFrancis-André Wollman

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