Translational regulation of environmental adaptation in bacteria.

The Journal of Biological Chemistry
Rodney Tollerson, Michael Ibba

Abstract

Bacteria must rapidly respond to both intracellular and environmental changes to survive. One critical mechanism to rapidly detect and adapt to changes in environmental conditions is control of gene expression at the level of protein synthesis. At each of the three major steps of translation-initiation, elongation, and termination-cells use stimuli to tune translation rate and cellular protein concentrations. For example, changes in nutrient concentrations in the cell can lead to translational responses involving mechanisms such as dynamic folding of riboswitches during translation initiation or the synthesis of alarmones, which drastically alter cell physiology. Moreover, the cell can fine-tune the levels of specific protein products using programmed ribosome pausing or inducing frameshifting. Recent studies have improved understanding and revealed greater complexity regarding long-standing paradigms describing key regulatory steps of translation such as start-site selection and the coupling of transcription and translation. In this review, we describe how bacteria regulate their gene expression at the three translational steps and discuss how translation is used to detect and respond to changes in the cellular environment. Fi...Continue Reading

References

Oct 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·F Lee, C Yanofsky
May 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·J P RichardsonC Lowery
Aug 5, 1992·Journal of Molecular Biology·O YarchukM Dreyfus
Jan 1, 1982·Annual Review of Genetics·R Kolter, C Yanofsky
Jan 1, 1994·Journal of Bacteriology·H S Cummings, J W Hershey
Mar 27, 1999·Journal of Bacteriology·A R Richardson, I Stojiljkovic
Jun 21, 2001·Proceedings of the National Academy of Sciences of the United States of America·T V PestovaC U Hellen
Mar 19, 2002·EMBO Reports·Pavel V BaranovJohn F Atkins
Aug 11, 2004·Proceedings of the National Academy of Sciences of the United States of America·Akiko MurakamiKoreaki Ito
Mar 10, 2005·Microbiology and Molecular Biology Reviews : MMBR·Brian Søgaard LaursenHans Uffe Sperling-Petersen
Jun 1, 2005·Biochimie·Michaël RyckelynckMagali Frugier
Sep 13, 2005·Annual Review of Microbiology·Wade C Winkler, Ronald R Breaker
Sep 14, 2006·Proceedings of the National Academy of Sciences of the United States of America·Pohl MilonClaudio O Gualerzi
Feb 13, 2007·Annual Review of Biochemistry·Sean D Moore, Robert T Sauer
Apr 24, 2008·Molecular Microbiology·Matthew F TraxlerTyrrell Conway
Aug 30, 2008·Journal of Molecular Biology·Chung-Jung TsaiRuth Nussinov
Dec 24, 2008·Proceedings of the National Academy of Sciences of the United States of America·Michael Y PavlovAnthony C Forster
Apr 22, 2009·Annual Review of Microbiology·Jiqiang LingMichael Ibba
Aug 27, 2009·Proceedings of the National Academy of Sciences of the United States of America·Jason M PetersRobert Landick
Oct 21, 2009·The Journal of Biological Chemistry·Douglas R TannerAllen R Buskirk
Mar 24, 2010·Proceedings of the National Academy of Sciences of the United States of America·So NakagawaTakashi Gojobori
Aug 16, 2011·Nature Chemical Biology·Hervé RoyMichael Ibba
May 1, 2012·Molecular Cell·Andrés Aguilera, Tatiana García-Muse
Jul 4, 2012·Annual Review of Microbiology·Emily J Capra, Michael T Laub
Jan 2, 2013·The Journal of Biological Chemistry·Tammy J BullwinkleMichael Ibba
Feb 23, 2013·Proceedings of the National Academy of Sciences of the United States of America·Christopher J WoolstenhulmeAllen R Buskirk
Sep 5, 2013·Proceedings of the National Academy of Sciences of the United States of America·Lauri PeilDaniel N Wilson
May 7, 2014·The Journal of Biological Chemistry·Alexandros D PetropoulosHani S Zaher
Jun 6, 2014·PLoS Genetics·Fabienne F V ChevanceKelly T Hughes
Aug 20, 2014·FEMS Microbiology Reviews·Agata L StarostaDaniel N Wilson
Aug 22, 2014·PLoS Genetics·Sara ElgamalMichael Ibba

❮ Previous
Next ❯

Citations

Nov 12, 2020·International Journal of Molecular Sciences·Laurence Despons, Franck Martin
Feb 2, 2021·Frontiers in Molecular Biosciences·Catherine E ScullNils G Walter
Dec 8, 2020·Biochemistry. Biokhimii︠a︡·K S UsachevSh Z Validov
Jun 14, 2021·Journal of Molecular Biology·Amr ElghondaklyWade C Winkler
Aug 28, 2021·International Journal of Molecular Sciences·Adamantia KouvelaVassiliki Stamatopoulou
Jan 6, 2022·Microbiology Spectrum·José Germán Serrano-GamboaMónica Noel Sánchez-González
Jan 20, 2022·Archives of Microbiology·Atif Khurshid WaniJuliana Heloisa Pinê Américo-Pinheiro

❮ Previous
Next ❯

Related Concepts

Related Feeds

ASBMB Publications

The American Society for Biochemistry and Molecular Biology (ASBMB) includes the Journal of Biological Chemistry, Molecular & Cellular Proteomics, and the Journal of Lipid Research. Discover the latest research from ASBMB here.

Related Papers

Progress in Molecular Biology and Translational Science
Chiara AmbrosiniAlessandro Quattrone
Wiley Interdisciplinary Reviews. RNA
Botao Liu, Shu-Bing Qian
Wiley Interdisciplinary Reviews. RNA
Douglas G MuenchMurtaza Dahodwala
© 2022 Meta ULC. All rights reserved