Translational Retinal Research and Therapies.

Translational Vision Science & Technology
Alison J HardcastleGustavo D Aguirre

Abstract

The following review summarizes the state of the art in representative aspects of gene therapy/translational medicine and evolves from a symposium held at the School of Veterinary Medicine, University of Pennsylvania on November 16, 2017 honoring Dr. Gustavo Aguirre, recipient of ARVO's 2017 Proctor Medal. Focusing on the retina, speakers highlighted current work on moving therapies for inherited retinal degenerative diseases from the laboratory bench to the clinic.

References

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Dec 22, 2004·Progress in Retinal and Eye Research·Andreas WenzelCharlotte E Remé
Mar 24, 2005·Proceedings of the National Academy of Sciences of the United States of America·Artur V CideciyanGustavo D Aguirre
May 27, 2005·Experimental Eye Research·Bryan W Jones, Robert E Marc
May 19, 2006·The British Journal of Ophthalmology·D M PaskowitzJ L Duncan
Nov 24, 2006·Cell Transplantation·András M KomáromyGustavo D Aguirre
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May 26, 2011·Molecular Therapy : the Journal of the American Society of Gene Therapy·Natalia CaporaleJohn G Flannery
Feb 7, 2012·Proceedings of the National Academy of Sciences of the United States of America·William A BeltranGustavo D Aguirre
Mar 5, 2013·Nature Neuroscience·Joshua LevitzEhud Y Isacoff
Sep 21, 2013·Investigative Ophthalmology & Visual Science·Orly GoldsteinGregory M Acland
Aug 7, 2014·Molecular Therapy : the Journal of the American Society of Gene Therapy·Emilie MacéDeniz Dalkara
Oct 28, 2014·Translational Vision Science & Technology·Brett G JeffreyPaul A Sieving
Dec 10, 2014·Proceedings of the National Academy of Sciences of the United States of America·Benjamin M GaubEhud Y Isacoff
Jul 4, 2015·Molecular Therapy : the Journal of the American Society of Gene Therapy·Benjamin M GaubJohn G Flannery
Aug 4, 2015·Current Biology : CB·Jasmina Cehajic-KapetanovicRobert J Lucas

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Citations

Nov 14, 2019·International Journal of Molecular Sciences·Alexander SumarokaSamuel G Jacobson
Aug 22, 2020·Translational Vision Science & Technology·Cord HuchzermeyerJan Kremers
Apr 22, 2021·The British Journal of Ophthalmology·Yu Fujinami-YokokawaUNKNOWN Japan Eye Genetics Study (JEGC) Group
Sep 16, 2021·Annual Review of Vision Science·Joo Yeun LeeFelice A Dunn

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Methods Mentioned

BETA
genotyping
gene replacement therapy

Clinical Trials Mentioned

NCT02317887

Software Mentioned

Streetlab
Gensight Biologics
Gensight

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