Translocation (6;9;22)(p25;q34;q11.2) identified by FISH in acute leukemia

Cancer Genetics and Cytogenetics
G J González, M Notohamiprodjo

Abstract

Fluorescence in situ hybridization (FISH) study of bone marrow cells from a patient with clinically and immunologically acute leukemia showed that an apparent t(6;22)(p25; q11.2) identified by routine banding techniques concealed a complex t(6;9;22)(p25;q34; q11.2). This observation further supports the importance of FISH in those cases where a chromosome rearrangement could not be reliably detected by conventional cytogenetic study.

References

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Citations

Jan 22, 2004·Cancer Genetics and Cytogenetics·Juan Pablo Meza EspinozaJuan Ramón González García
Oct 29, 2002·Leukemia & Lymphoma·Subramaniyam ShivakumarAlok Srivastava

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