Transmission and scanning electron microscope studies of calcified cartilage resorption

The Anatomical Record
I Savostin-Asling, C W Asling

Abstract

The authors' previous report (Savostin-Asling and Asling, '73) demonstrated that Meckel's carilage is a favorable site for study of calcified cartilage resorption. In the present study the ultrastructural features at this resorption front have been examined by transmission and scanning electron microscopes (19-day rat retus). Multinucleated giant cells chondroclasts) dominated the erosion front. The many features which they showed in common with osteoclasts included abundant mitochondria, vacuolation, lysonsomes, sparsity of rough-sufaced endoplasmic reticulum, and deep infoldings at loci of contact with calcified matrix. Crumbling of matrix (with mineral crystals penetrating between these foldings) and fragmentation of collagen fibrils were also seen. The propensity of chondroclasts for spanning several opened lacunae provided special opportunity to demonstrate cell surface modifications in presence or absence of matrix contact. Amebiod processes extending into lacunae were seen by both transmission and scanning procedures; they were sometimes tipped with a veil of filamentous processes as small as 0.3 mum in diameter. Most hypertrophic chondrocytes. when released from lacunae, appeared to be disintegrating. However, in accord...Continue Reading

References

Jul 1, 1973·The Anatomical Record·I Savostin-Asling, C W Asling
Jan 1, 1970·International Review of Cytology·M Owen
Dec 28, 1968·Nature·M Owen, M R Shetlar
Jul 1, 1967·The Journal of Cell Biology·R K SchenkJ Wiener
Jul 1, 1960·Archives of Oral Biology·S TAKUMA
May 1, 1960·The Journal of Bone and Joint Surgery. British Volume·J TRUETA, K LITTLE
Dec 1, 1961·The Journal of Biophysical and Biochemical Cytology·N M HANCOX, B BOOTHROYD
Jul 1, 1962·Journal of Dental Research·S TAKUMA
Nov 1, 1950·The American Journal of Anatomy·M HELLERW BLOOM
Dec 15, 1949·The Journal of Physiology·N M HANCOX
Sep 25, 1964·Science·C E Hall

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Citations

Sep 1, 1990·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·C E FarnumN J Wilsman
Jan 1, 1986·Tissue & Cell·D ChappardG Riffat
Dec 3, 2002·Tissue Engineering·Kimberly M SpangenbergLawrence J Bonassar
Jul 14, 2006·Anatomia, histologia, embryologia·M R B EslaminejadP E Yazdi
Jan 1, 1981·Journal of Ultrastructure Research·K S Lester, M M Ash
Oct 1, 1985·The American Journal of Anatomy·A A Cole, F H Wezeman
Nov 1, 1987·The Anatomical Record·C E Farnum, N J Wilsman
Apr 3, 2019·Nature Cell Biology·Jameel Iqbal, Mone Zaidi
Sep 29, 2020·Frontiers in Cell and Developmental Biology·Eva SvandovaEva Matalova
Jan 6, 2021·Histochemistry and Cell Biology·Yasuhiko BandoOsamu Amano
Aug 20, 2021·Journal of Structural Biology·Neta VarsanoSteve Weiner

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