Transmission dynamics of a multidrug-resistant Salmonella typhimurium outbreak in a dairy farm.

Foodborne Pathogens and Disease
C LanzasY T Gröhn

Abstract

Cattle are recognized as an important source of foodborne Salmonella causing human illness, particularly for antimicrobial-resistant strains. The transmission dynamics of multidrug-resistant (MDR) Salmonella after the onset of a clinical outbreak in a dairy farm has been rarely monitored. The early transmission of a pathogen influences the outbreak size and persistence of the pathogen at the farm level and, therefore, how long the herd represents a risk for Salmonella zoonotic transmission. The objective of this study was to describe the transmission dynamics of MDR Salmonella Typhimurium after the onset of a clinical outbreak in a dairy herd. For that purpose, fecal shedding and serological response to MDR Salmonella were monitored in a longitudinal study conducted in a dairy herd after a few cases of salmonellosis, and a stochastic transmission model was developed to predict Salmonella persistence at the pen level. The outbreak was limited to five clinical cases, and only 18 animals out of 500 cows shed Salmonella in feces. The longest shedder was culture-positive for Salmonella for at least 68 days. The isolates (n = 27) were represented by four pulsed-field gel electrophoresis patterns; three patterns were similar. With one...Continue Reading

References

Jan 13, 2001·Clinical Neurology and Neurosurgery·J C SarriaR C Kimbrough
Nov 29, 2001·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·J K HouseD Kamiya
Nov 7, 2002·Journal of the American Veterinary Medical Association·Carla L HustonBrenda C Love
Jan 19, 2005·The Journal of Infectious Diseases·Jay K VarmaFrederick J Angulo
Feb 16, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Amy M DechetUNKNOWN Multistate Working Group
Feb 16, 2006·Journal of the American Veterinary Medical Association·Rowland N CobboldDale D Hancock
Mar 15, 2006·Mathematical Biosciences·Y XiaoR G Bowers
Sep 9, 2008·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Brenda C Love, Marcos H Rostagno
Jul 22, 2009·Journal of Dairy Science·K J CummingsK E Reed

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Citations

Mar 8, 2011·Applied and Environmental Microbiology·Lisa GorskiRobert E Mandrell
Mar 1, 2014·Bulletin of Mathematical Biology·Zhao LuYnte H Schukken
Oct 30, 2016·Critical Reviews in Food Science and Nutrition·Kristi L HelkeBernadette P Marriott
Dec 16, 2018·International Journal of Environmental Research and Public Health·Asja KorajkicValerie J Harwood
Jun 3, 2021·Poultry Science·Rim El JeniTodd R Callaway

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Methods Mentioned

BETA
blood collection
enzyme-linked immunosorbent assay
electrophoresis

Software Mentioned

BioNumerics
DeclareMathSizes

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