Transmission electron and high-voltage electron microscopy of osteocyte cellular processes extending to the dental implant surface

Journal of Biomedical Materials Research
D E SteflikP Brewer

Abstract

Examination of the morphology of osteocytes within the bone supporting endosteal dental implants was performed using conventional transmission and high-voltage transmission electron microscopy (HVEM). The in vivo dog model used 72 implants inserted into the premolar region of 18 experimental animals. Forty-eight implants in 12 dogs were used as anterior abutments for fixed bridges for periods up to 12 months. The mineralized matrix of the supporting bone was either directly apposed to the implant surface or was separated from the implant by a narrow region of unmineralized matrix. Osteocytes were routinely observed to be closely associated with the bone-implant interface, as well as at a distance from the implant. Osteocytes were found to extend cellular processes directly to the implant surface through canaliculi. The osteocyte processes contained microfilaments. The three-dimensional capabilities of HVEM elucidated the nature of these cell processes at the point of exit from the osteocyte, as the processes extended through the mineralized matrix, and as the processes terminated at the implant interface. This report suggests that avenues of communication may exist between the implant and the osseous cells, providing intriguing...Continue Reading

References

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Citations

Mar 10, 1998·Journal of Biomedical Materials Research·D E SteflikD J Berkery
May 1, 1996·Journal of Dentistry·D BrownD Wood
Feb 1, 1996·Journal of Oral Rehabilitation·J C Wataha
Feb 26, 2005·Clinical and Experimental Pharmacology & Physiology·Iven Klineberg
May 25, 1999·Periodontology 2000·S G Steinemann
Apr 18, 2012·Journal of Oral Rehabilitation·I J KlinebergG M Murray
Oct 8, 2014·Journal of Orthopaedic Surgery and Research·Arihiko KanajiKotaro Sena
Nov 24, 1998·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·M M KlingerJ E Lemons
Mar 30, 2001·Advances in Dental Research·D E SteflikG R Parr
Dec 24, 2018·Journal of Biomedical Materials Research. Part a·Yoko TakemuraKiyoshi Koyano
May 28, 2004·The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology·Li-Dan YouMitchell B Schaffler

Related Concepts

Canis familiaris
Electron Microscopy
Osteocytes
Randomization
Surface Properties
Dental Prostheses, Surgical

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