Transmission Imaging in Lymphoscintigraphy with a 153Gd Flood Source

Journal of Nuclear Medicine Technology
Frank P DiFilippoDonald R Neumann

Abstract

Lymphoscintigraphy uses intradermal or interstitial injections of (99m)Tc-labeled tracers to produce images of focal lymph nodes. Because there is little or no anatomic information in the (99m)Tc images, a (57)Co flood source is sometimes used to provide transmission data along with the emission data. The anatomic shadow from the transmission scan generally improves interpretation and surgical planning. However, the (57)Co transmission photons contribute to background on the (99m)Tc images, reducing contrast and signal-to-noise ratio (SNR). SNR is related to lesion detection, and some lymph nodes that would be detected in an emission-only scan might not be detected if acquired with a (57)Co flood source. An alternative to a (57)Co flood source is a (153)Gd flood source, which has primary photon emissions well below the (99m)Tc emission window, allowing the shadow to be acquired in a separate transmission window. Significantly smaller crosstalk from (153)Gd should improve SNR and therefore would be expected to improve lymph node detection. We hypothesized that the use of a (153)Gd flood source would reduce background and improve SNR for these studies. Phantom studies simulating lymphoscintigraphy were performed to compare perfor...Continue Reading

References

May 25, 2004·Nuclear Medicine Communications·Brigitte WilczekHans Jacobsson
May 17, 2008·Journal of Nuclear Medicine Technology·Martha V MarRichard E Wendt
Oct 3, 2013·European Journal of Nuclear Medicine and Molecular Imaging·Francesco GiammarileSergi Vidal Sicart

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