Transmission of African swine fever virus from infected pigs by direct contact and aerosol routes

Veterinary Microbiology
Ann Sofie OlesenAnette Bøtner

Abstract

In 2014, African swine fever virus (ASFV) was introduced into the Baltic states and Poland. Since then, the disease has continued to spread within these regions, and recently, cases were reported in the Czech Republic and Romania. Currently, there is an increasing risk of ASFV introduction into Western Europe. Hence, there is an urgent need to assess current contingency plans. For this purpose, knowledge of modes-of-transmission and clinical outcome in pigs infected with new European ASFV strains is needed. In the present study, two experiments were conducted in pigs using an isolate of ASFV from Poland (designated here POL/2015/Podlaskie/Lindholm). In both studies, pigs were inoculated intranasally with the virus and contact pigs were exposed to the experimentally infected pigs, either directly (contact within and between pens) or by air. Pigs exposed to the virus by intranasal inoculation, by direct contact to infected animals and by aerosol developed acute disease characterized by viremia, fever and depression. Infectious virus was first detected in blood obtained from the inoculated pigs and then sequentially among the within-pen, between-pen and air-contact pigs. ASFV DNA and occasionally infectious virus was found in nasa...Continue Reading

Citations

Jun 8, 2018·Transboundary and Emerging Diseases·Ann Sofie OlesenRené Bødker
Feb 20, 2018·Transboundary and Emerging Diseases·A S OlesenA Bøtner
Mar 23, 2019·Emerging Microbes & Infections·Dongming ZhaoZhigao Bu
Sep 20, 2019·Viruses·Katja SchulzCarola Sauter-Louis
Oct 2, 2019·Journal of Veterinary Research·Natalia Mazur-PanasiukGrzegorz Woźniakowski
Mar 10, 2020·Transboundary and Emerging Diseases·Ann Sofie OlesenAnette Bøtner
Jun 2, 2020·Frontiers in Veterinary Science·Natasha N GaudreaultJuergen A Richt
Aug 5, 2020·Transboundary and Emerging Diseases·Céline FaverjonAngus Cameron
Nov 29, 2018·EFSA Journal·UNKNOWN European Food Safety Authority (EFSA)Christian Gortázar
Oct 17, 2020·Frontiers in Veterinary Science·Tariq HalasaCarsten Kirkeby
Apr 4, 2021·Animals : an Open Access Journal From MDPI·Megan C Niederwerder
May 1, 2021·Preventive Veterinary Medicine·Brandon H HayesTimothée Vergne
Jun 20, 2021·Transboundary and Emerging Diseases·Nina MatsumotoStuart D Blacksell
Sep 4, 2021·Journal of Medical Microbiology·Andrew D Wales, Robert H Davies
Dec 8, 2021·Animal Biotechnology·Cheng-Xing LongZhou-Jin Tan

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