Transmission of herpes simplex virus Type 2 among factory workers in Ethiopia

The Journal of Infectious Diseases
Yenew KebedeNicole H T M Dukers

Abstract

The herpes simplex virus type 2 (HSV-2) and human immunodeficiency virus (HIV) epidemics are believed to fuel each other, especially in sub-Saharan countries. In Ethiopia during 1997-2002, a retrospective study was conducted to examine risk factors for infection and transmission of HSV-2, in a cohort of 1612 factory workers. Prevalence of HSV-2 seropositivity at enrollment was 40.9%, and incidence of seroconversion was 1.8 seroconversions/100 person-years (PY), which decreased over time. Independent risk factors for seropositivity were having an HSV-2-seropositive partner, female sex, HIV antibodies, positive Treponema pallidum particle agglutination assay result, older age, low education level, and orthodox religion. These same factors were independent risk factors for HSV-2 seroconversion, with the exception of the latter 3. Most HSV-2-infected persons did not report symptoms. Among 41 monogamous HSV-2-serodiscordant heterosexual couples, incidence of HSV-2 seroconversion was 20.75 seroconversions/100 PY for women and 4.93 seroconversions/100 PY for men. The high burden of both HSV-2 and HIV infection in Ethiopia warrants stringent control measures.

Citations

Nov 1, 2008·BMC Women's Health·Eugene J KongnyuyBella Adler
Sep 13, 2006·BMC International Health and Human Rights·Eugene J KongnyuyLuc Kouam
Aug 9, 2007·BMC International Health and Human Rights·Eugene J Kongnyuy, Charles Shey Wiysonge
Mar 17, 2011·BMC Research Notes·Andrew MujugiraJairam Lingappa
Mar 4, 2015·Open Forum Infectious Diseases·Sharanya RajagopalAnna Wald
Sep 11, 2020·International Journal of Microbiology·Daniel Hussien RetaFisseha Alemu Reta

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