Transmission rates, screening methods and costs of MRSA--a systematic literature review related to the prevalence in Germany.

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
A TübbickeS Fleßa

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) infections represent a serious challenge for health care institutions, which is inherent in the combination of prevalence, transmission rates and costs. Furthermore, performing an MRSA screening requires information on the complex system of effectiveness, accuracy and costs of different screening methods. The purpose of this study was to give an overview of parameters with decisive significance for the burden of MRSA and the selection of a specific MRSA screening strategy. A systematic literature search for peer-reviewed health economic studies associated with MRSA was performed (from 1995 to the present). Eighty-seven different studies met all inclusion and exclusion criteria. Primary outcomes included the prevalence of MRSA, MRSA transmission rates, performance characteristics of MRSA screening methods, costs for pre-emptive isolation precautions and costs per MRSA case. The prevalence rates reported for all inpatients (1.2-5.3 %) as well as for inpatients with risk factors or patients in risk areas (3.85-20.6 %) vary greatly. The range of cross-transmission rates per day reported for patients with MRSA in isolation is 0.00081-0.009 and for carriers not in isolation is 0.0013...Continue Reading

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Citations

Jun 16, 2012·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·C HübnerS Fleßa
Dec 4, 2012·BMC Health Services Research·Andrea TübbickeSteffen Fleßa
Sep 4, 2014·Asian Pacific Journal of Tropical Biomedicine·Abazar PournajafHassan Abbaszadeh
Dec 5, 2015·Antimicrobial Resistance and Infection Control·Claudia HübnerSteffen Flessa
Dec 17, 2017·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Claudia HübnerSteffen Flessa
Sep 26, 2019·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Anders Skyrud DanielsenOliver Kacelnik

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