Transoesophageal cardiac pacing is effective for cardiopulmonary resuscitation in a rat of asphyxial model

Resuscitation
Feng-Qing SongMeng-Hua Chen

Abstract

To investigate effectiveness of transoesophageal cardiac pacing in a rat model of asphyxial cardiac arrest. Ten minutes after the tracheal tube had been clamped, cardiac arrest (CA) occurred in 20 Sprague-Dawley rats, and the rats were assigned randomly to receive cardiopulmonary resuscitation (CPR) in a control group or CPR combined with transoesophageal cardiac pacing in a pacing group. Restoration of spontaneous circulation (ROSC) was defined as an unassisted pulse with a mean arterial pressure (MAP) of >or=20 mmHg for >or=1 min. ROSC was significantly more frequent in the pacing group compared with the control group (7/10 versus 1/10, P<0.05). Faster ROSC and longer survival trend in the pacing group were seen compared with the control group. Transoesophageal cardiac pacing is effective for CPR in a rat of asphyxial model. However, the precise mechanism is not clear and further experiments will be necessary.

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Citations

Oct 7, 2011·Annals of Pediatric Cardiology·Hiren N Doshi, Seema T Lokare
Mar 13, 2010·The American Journal of Emergency Medicine·Meng-Hua ChenFeng-Qing Song
Oct 28, 2009·The American Journal of Emergency Medicine·Meng-Hua ChenXiao-Fen Tian
Nov 21, 2007·The American Journal of Emergency Medicine·Meng-Hua ChenShu-Rong Mo
Jul 4, 2007·The American Journal of Emergency Medicine·Meng-Hua ChenShu-Rong Mo
Jun 15, 2007·Resuscitation·Meng-Hua ChenZhi-Yu Zeng
Aug 30, 2006·The American Journal of Emergency Medicine·Meng-Hua ChenTao He

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