Transoral Endoscopic Head and Neck Surgery and Its Role Within the Multidisciplinary Treatment Paradigm of Oropharynx Cancer: Robotics, Lasers, and Clinical Trials

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
F Christopher Holsinger, Robert L Ferris

Abstract

Transoral endoscopic head and neck surgery is a new approach for the treatment of oropharyngeal tumors. Using either a robotic system and/or laser, surgeons gain access through the mouth via minimally invasive technique and thus have improved visualization of the tumors of the oropharynx, without disfiguring incisions. This transoral route of access minimizes long-term speech and swallowing dysfunction. Surgeons view this approach as a considerable technologic advance, analogous to the evolution in radiation therapy from conventional two- and three-dimensional conformal techniques to intensity-modulated techniques. Although the use of radiation with or without chemotherapy to treat oropharyngeal cancer (OPC) is supported by evidence from prospective clinical trials, there are no prospective data supporting the use of this new surgical approach for OPC. Here, we review the fundamentals of transoral endoscopic head and neck surgery, with robotics and laser technology, and discuss ongoing clinical trials for patients with OPC.

References

Dec 1, 1972·The Annals of Otology, Rhinology, and Laryngology·M S Strong, G J Jako
Mar 3, 2001·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·W SteinerM Kron
Oct 1, 1964·American Journal of Surgery·A J BALLANTYNE
Jul 20, 2005·Archives of Otolaryngology--head & Neck Surgery·F Christopher HolsingerOllivier Laccourreye
May 3, 2007·The Laryngoscope·C Arturo Solares, Marshall Strome
Oct 18, 2007·International Journal of Radiation Oncology, Biology, Physics·F Christopher Holsinger, Randal S Weber
Dec 19, 2007·Archives of Otolaryngology--head & Neck Surgery·Gregory S WeinsteinHarry Quon
Jun 19, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Mitchell MachtayK Kian Ang
Aug 1, 2009·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Tim A IseliJ Scott Magnuson
Apr 29, 2010·Current Oncology Reports·Floyd Christopher HolsingerDavid G Grant
Jun 10, 2010·The New England Journal of Medicine·K Kian AngMaura L Gillison
Jun 30, 2010·The Annals of Otology, Rhinology, and Laryngology·David O FrancisBevan Yueh
Nov 17, 2010·Archives of Otolaryngology--head & Neck Surgery·Adam S GardenRandal S Weber
Dec 7, 2010·The Journal of the Royal College of Physicians of Edinburgh·R J Casasola
Dec 22, 2010·Archives of Otolaryngology--head & Neck Surgery·Hilliary N WhiteJ Scott Magnuson
Jul 13, 2011·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Janet A WilsonJoanne M Patterson
Oct 5, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Anil K ChaturvediMaura L Gillison
Feb 22, 2012·Archives of Otolaryngology--head & Neck Surgery·Kathryn M Van AbelKerry D Olsen
Jun 13, 2012·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Randall P Morton
Jul 4, 2012·The Laryngoscope·Gregory S WeinsteinF Christopher Holsinger
Jul 18, 2012·Archives of Otolaryngology--head & Neck Surgery·Gregory S WeinsteinBert W O'Malley
Apr 12, 2013·JAMA Otolaryngology-- Head & Neck Surgery·Peter T DziegielewskiEnver Ozer
May 4, 2013·Cancer·Katherine A HutchesonF Christopher Holsinger
Aug 21, 2013·JAMA Otolaryngology-- Head & Neck Surgery·Hilliary WhiteJ Scott Magnuson
Nov 20, 2013·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Anil K ChaturvediMaura L Gillison
Mar 20, 2014·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Katherine A HutchesonJan S Lewin
Jan 7, 2015·CA: a Cancer Journal for Clinicians·Rebecca L SiegelAhmedin Jemal
Apr 4, 2015·JAMA Otolaryngology-- Head & Neck Surgery·Garret W ChobyUmamaheswar Duvvuri

❮ Previous
Next ❯

Citations

Apr 28, 2016·Current Treatment Options in Oncology·J Kenneth Byrd, Robert L Ferris
Jun 18, 2016·The Laryngoscope·Raymond K Tsang, F Christopher Holsinger
Aug 18, 2016·Oral Oncology·Matthew C Ward, Shlomo A Koyfman
Sep 10, 2015·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Danny RischinQuynh-Thu Le
May 10, 2017·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Catherine H FrenkelGhassan J Samara
Jul 7, 2017·The Laryngoscope·Michelle M ChenF Christopher Holsinger
May 10, 2017·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Tuan-Jen FangHui-Chen Chiang
Nov 29, 2017·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Michael J PerskyRobert L Ferris
Nov 21, 2017·The Laryngoscope·Michael C TopfAdam J Luginbuhl
Dec 13, 2016·The Cochrane Database of Systematic Reviews·James HowardChris Nutting
Nov 8, 2018·ORL; Journal for Oto-rhino-laryngology and Its Related Specialties·Ryan K OroscoF Christopher Holsinger
Feb 8, 2019·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Lauri JouhiHarri Keski-Säntti
Feb 24, 2019·Japanese Journal of Clinical Oncology·Meijin NakayamaRyan K Orosco
Feb 28, 2019·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Shlomo A KoyfmanF Christopher Holsinger
Jul 3, 2019·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·Susanne FlachJaiganesh Manickavasagam
Nov 22, 2017·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Carole FakhryDavid W Eisele
Dec 14, 2019·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Alexander Fabian, David Krug
Nov 2, 2019·The Annals of Otology, Rhinology, and Laryngology·Meijin NakayamaNobuhiko Oridate
Nov 22, 2019·Head & Neck·Philippe GorpheAntoine Moya-Plana
Jul 10, 2020·Current Oncology Reports·Renan Bezerra Lira, Luiz Paulo Kowalski
Sep 5, 2018·Annals of the Royal College of Surgeons of England·George Garas, Neil Tolley
May 28, 2020·Japanese Journal of Clinical Oncology·Fumihiko MatsumotoSeiichi Yoshimoto
Aug 31, 2020·The Oncologist·Ari J Rosenberg, Everett E Vokes
Nov 20, 2016·Journal of Oncology Practice·Meghan T TurnerRobert L Ferris
Dec 3, 2016·Nature Reviews. Disease Primers·Mark SchiffmanSilvia Franceschi
Mar 27, 2018·The Laryngoscope·Shamik MascharakF Christopher Holsinger

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

Related Papers

Otolaryngologic Clinics of North America
Ryan J Li, Jeremy D Richmon
Rambam Maimonides Medical Journal
Shivani Shah, David Goldenberg
Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists
Eric J MooreJan L Kasperbauer
© 2021 Meta ULC. All rights reserved