PMID: 108647Jun 1, 1979

Transplantation of hamster buccal pouch carcinoma to neonatal hamsters

Oral Surgery, Oral Medicine, and Oral Pathology
L P MerkJ Albright


Epidermoid carcinomas of oral mucosa were induced with DMBA in the buccal pouches of hamsters. The well-differentiated primary tumors were allografted into the peritoneal cavities of neonatal hamsters that had been treated with antilymphocyte serum. Solid tumors grew rapidly in the peritoneum and were harvested 6 to 31 days postimplantation. Gross and histopathologic specimens revealed infiltrative masses of tumor that had become more anaplastic than the original tumor. This in vivo model has considerable potential as a means of studying the immunology of oral cancers during tumor progression.


Apr 1, 1977·Oral Surgery, Oral Medicine, and Oral Pathology·E Eisenberg, G Shklar
Mar 1, 1971·Oral Surgery, Oral Medicine, and Oral Pathology·J L Giunta, G Shklar
Apr 1, 1954·Journal of Dental Research·J J SALLEY
Jan 1, 1961·Journal of Dental Research·A L MORRIS
Nov 1, 1963·Oral Surgery, Oral Medicine, and Oral Pathology·S SILBERMAN, G Shklar
Feb 1, 1964·Oral Surgery, Oral Medicine, and Oral Pathology·H SANTISH H CHAUNCEY


Related Concepts

Abdominal Neoplasms
Squamous Cell Carcinoma
Cheek Structure
Malignant Neoplasm of Mouth
Neoplasm Transplantation
Neoplasms, Experimental
Peritoneal Neoplasms

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