Transplantation tolerance from a historical perspective

Nature Reviews. Immunology
T E Starzl, R M Zinkernagel

Abstract

Although transplantation immunology as a distinctive field began with the development of experimental models that showed the feasibility of bone marrow transplantation, organ engraftment was accomplished first in humans, and was thought for many years to occur by drastically different mechanisms. Here, we present our view of the concepts of allograft acceptance and acquired tolerance from a historical perspective, and attempt to amalgamate them into simple and unifying rules that might guide improvements in clinical therapy.

References

Apr 24, 1975·The New England Journal of Medicine·E D ThomasC D Buckner
Jun 27, 1992·Lancet·T E StarzlM Trucco
Jan 1, 1967·Advances in Immunology·J Sterzl, A M Silverstein
Jul 1, 1968·The Journal of Experimental Medicine·C F Barker, R E Billingham
Jan 1, 1968·Advances in Immunology·D W Dresser, N A Mitchison
Jan 1, 1983·Annual Review of Immunology·K J LaffertyH S Warren
Jun 1, 1995·Clinical Transplantation·H C BodenheimerP Sheiner
Jun 1, 1993·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·T E StarzlJ J Fung
Jan 12, 1996·Science·R M Zinkernagel
Dec 1, 1996·Immunology Today·T E StarzlA S Rao
Dec 1, 1996·Immunology Today·K Wood, D H Sachs
Jan 1, 1997·Immunology Today·R M Zinkernagel, P C Doherty
Dec 24, 1998·The New England Journal of Medicine·T E Starzl, R M Zinkernagel
Nov 5, 1999·Nature Medicine·H Waldmann
Jun 3, 2000·Annual Review of Immunology·E M Shevach
Nov 21, 2000·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·N IchikawaN Murase
Jan 3, 2001·Nature Medicine·C C Anderson, P Matzinger
May 5, 2001·Immunity·R LechlerR M Steinman
Aug 15, 2001·Transplantation·M TakatsukiK Tanaka
Jun 13, 1959·Nature·R SCHWARTZ, W DAMESHEK
Nov 1, 1960·The British Journal of Surgery·N G ROTHNIEJ B KINMONTH
Jun 13, 1963·The New England Journal of Medicine·J E MURRAYG J DAMMIN
May 31, 1960·Annals of the New York Academy of Sciences·M SIMONSEN
Sep 1, 1962·Postgraduate Medical Journal·R KUSSM CAMEY
Oct 1, 1934·Annals of Surgery·H B StoneG O Gey

❮ Previous
Next ❯

Citations

May 21, 2009·JAMA : the Journal of the American Medical Association·Thomas E Starzl, Clyde Barker
Feb 18, 2004·Transplant Immunology·Seiichiro InoueEiji Kobayashi
Jul 5, 2003·The Journal of Surgical Research·Rebecca A SchroederPaul C Kuo
May 10, 2003·Lancet·Thomas E StarzlJohn J Fung
Jul 25, 2003·Human Immunology·Diana MetesNoriko Murase
Jul 19, 2005·Nature Reviews. Molecular Cell Biology·Martin Evans
Aug 26, 2010·Nature Reviews. Nephrology·Maarten Naesens, Minnie M Sarwal
Jan 25, 2008·The New England Journal of Medicine·Thomas E Starzl
Dec 25, 2003·The Proceedings of the Nutrition Society·Kareem Abu-Elmagd, Geoffrey Bond
Aug 10, 2004·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Hargovind L TrivediVarsha B Trivedi
May 10, 2005·Transplantation·Thomas E Starzl
Apr 13, 2004·Transplantation·Thomas E StarzlJohn J Fung
Apr 13, 2004·Transplantation·Joshua MillerViolet Esquenazi
Sep 25, 2012·Annals of Surgery·Stefan SchneebergerW P Andrew Lee
May 17, 2006·Clinical and Experimental Pharmacology & Physiology·John M Luk, Kwong-Fai Wong
Dec 20, 2012·Clinical & Developmental Immunology·Kadiyala V RavindraSuzanne T Ildstad
Apr 18, 2007·Biology Direct·William F N ChanColin C Anderson
Apr 22, 2006·BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy·Gaetano CiancioJoshua Miller
Apr 20, 2011·Paediatric Drugs·Navdeep S NayyarGeorge V Mazariegos
Oct 10, 2013·World Journal of Gastroenterology : WJG·Sheng-Li Wu, Cheng-En Pan
Sep 10, 2013·International Urology and Nephrology·Selcuk KilincCezmi Karaca
Aug 21, 2004·Proceedings of the National Academy of Sciences of the United States of America·Thomas E Starzl
Jul 16, 2014·Clinics in Liver Disease·Paige M PorrettAbraham Shaked
Jul 18, 2002·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·P Toby H Coates, Angus W Thomson
Nov 18, 2009·Transplantation Proceedings·K V RavindraS T Ildstad
Oct 21, 2005·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Bijan EghtesadThomas E Starzl
Aug 17, 2004·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·George V MazariegosJorge Reyes
Mar 3, 2005·Clinical Transplantation·Nicola De RuvoAntonio Daniele Pinna

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.