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Transposable elements have contributed human regulatory regions that are activated upon bacterial infection

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences

Feb 23, 2020

Lucia BogdanGuillaume Bourque

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Abstract

Transposable elements (TEs) are increasingly recognized as important contributors to mammalian regulatory systems. For instance, they have been shown to play a role in the human interferon response, but their involvement in other mechanisms of immune cell activation remains poorly under...read more

Mentioned in this Paper

Analysis
Quantitative Trait Loci
Transcription Factor
Macrophage
Dalfampridine
Trinucleotide Repeats
Immune Cell Activation Process
Bacterial Infections
Immune Response
NF-kappa B
Paper Details
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Transposable elements have contributed human regulatory regions that are activated upon bacterial infection

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences

Feb 23, 2020

Lucia BogdanGuillaume Bourque

PMID: 32075553

DOI: 10.1098/rstb.2019.0332

Abstract

Transposable elements (TEs) are increasingly recognized as important contributors to mammalian regulatory systems. For instance, they have been shown to play a role in the human interferon response, but their involvement in other mechanisms of immune cell activation remains poorly under...read more

Mentioned in this Paper

Analysis
Quantitative Trait Loci
Transcription Factor
Macrophage
Dalfampridine
Trinucleotide Repeats
Immune Cell Activation Process
Bacterial Infections
Immune Response
NF-kappa B

Feeds With Similar Papers

Transposons for Gene Editing

Transposons can replicate and spread through the host’s genome and therefore be used as a genetic tool for analysis of gene function. Discover the latest research on the use of transposons for gene editing here.

Copy Number Variation

Copy number variation refers to alterations in the number of gene copies or DNA sequences. It can be a duplication, amplification, or a deletion event. Here is the latest research.

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