Transposable elements: how non-LTR retrotransposons do it

Current Biology : CB
D J Finnegan

Abstract

The source of the enzyme activity responsible for the transposition of retrotransposons of the type that lack terminal repeats has at last been identified: in L1Hs elements, it is encoded by the second open reading frame and is a nuclease related to the apurinic repair endonucleases.

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