Transrectal ultrasound versus magnetic resonance imaging for detection of rectal wall invasion by prostate cancer

The Prostate
Dan LeiboviciLouis L Pisters

Abstract

This study compared the accuracy of transrectal ultrasound (TRUS) versus magnetic resonance imaging (MRI) in the detection of rectal wall involvement by prostate cancer in patients undergoing salvage total pelvic exenteration (TPE) or cystoprostatectomy. We identified 16 patients who underwent TPE and 24 patients who underwent cystoprostatectomy for locally advanced prostate cancer as salvage procedures with palliative intent. Patients were examined by TRUS, MRI, or both within the month preceding surgery. Histologic evidence of rectal involvement with prostate cancer was considered the gold standard diagnostic criterion in patients undergoing TPE. Among patients undergoing cystoprostatectomy, posterior prostatic surgical margins and clinical evidence of rectal wall recurrence during a median follow-up duration of 18.6 months were considered the gold standard. The sensitivity, specificity, and overall accuracy with which TRUS and MRI detected rectal wall involvement were compared. Fifteen (93.7%) of the patients who underwent TPE had histologically-proven rectal wall involvement with prostate cancer. Rectal and perineal recurrence developed 10 months after surgery in 1 (4.1%) patient in the cystoprostatectomy group. The sensiti...Continue Reading

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Citations

Jan 20, 2012·Der Urologe. Ausg. A·G SchöpplerA E Pelzer
Apr 25, 2006·Current Urology Reports·Philippe E SpiessLouis L Pisters
Sep 26, 2007·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·D FischerovaJ Belacek
Oct 1, 2008·Der Urologe. Ausg. A·F C von RundstedtS Roth
Dec 10, 2008·Current Problems in Cancer·John F WardLouis L Pisters
Feb 27, 2007·Gastrointestinal Endoscopy·Everson L A ArtifonManoop S Bhutani
Apr 25, 2006·The Urologic Clinics of North America·Michael J ManyakErik S Storm
Apr 17, 2007·BJU International·Michael MitterbergerWolfgang Horninger
Nov 11, 2009·Pathology·Charles C GuoPatricia Troncoso

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