Abstract
The purpose of this study was to measure the local electrical field or potential gradient, measured with a catheter-based system, required to terminate long duration electrically or ischaemically induced ventricular fibrillation (VF). We hypothesized that prolonged ischaemic VF would be more difficult to terminate when compared to electrically induced VF of similar duration. Thirty anesthetized and instrumented swine were randomized to electrically induced VF or spontaneous, ischaemically induced VF, produced by balloon occlusion of the left anterior descending coronary artery. After 7 min of VF, chest compressions were initiated and rescue shocks were attempted 1 min later. The potential gradient for each shock was measured and the mean values required for defibrillation compared for the VF groups. The number of shocks and the shock strength required for termination of VF were not significantly different for the groups. The potential gradient of the first successful defibrillating shock was significantly greater in the spontaneous, occlusion-induced VF group (12.80+/-2.82 V/cm vs 9.60+/-2.48 V/cm, p=0.002). The number of refibrillations was greater in the ischaemic group than in the non-ischaemic electrical group (6+/-4 vs 1+/...Continue Reading
References
Sep 1, 1986·Circulation·P S ChenR E Ideker
Sep 1, 1981·The American Journal of Cardiology·P OuyangP J Varghese
Dec 31, 1997·Circulation·D MehtaV Fuster
Nov 17, 1998·Circulation·G P WalcottR E Ideker
Sep 17, 1999·Resuscitation·B E Gliner, R D White
Jan 15, 2002·Journal of the American College of Cardiology·Gregory P WalcottRaymond E Ideker
May 30, 2002·Circulation·Hao QinRaymond E Ideker
Jun 4, 2004·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·James T NiemannRobert G Walker
Feb 5, 2005·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·James T NiemannJohn P Rosborough
Jan 13, 2006·Circulation·Thomas ThomUNKNOWN American Heart Association Statistics Committee and Stroke Statistics Subcommittee
Dec 1, 2006·Resuscitation·Jinglan WangLei Huang
Mar 7, 2007·Pacing and Clinical Electrophysiology : PACE·John P RosboroughJames T Niemann
Apr 7, 2007·Critical Care Medicine·James T NiemannRoger J Lewis
Jan 22, 2008·Resuscitation·Douglas ChamberlainAndrew Smith
Sep 25, 2008·JAMA : the Journal of the American Medical Association·Graham NicholUNKNOWN Resuscitation Outcomes Consortium Investigators
Oct 31, 2008·Resuscitation·Jerry P NolanTerry Vanden Hoek
Nov 6, 2008·Heart Rhythm : the Official Journal of the Heart Rhythm Society·James D AllredGregory P Walcott