Transthoracic echocardiographic measurement of coronary blood flow and reserve

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
J J Crowley, L M Shapiro

Abstract

The objectives of this study were to evaluate the use of high-frequency (5 MHz) transthoracic echocardiography for the noninvasive measurement of coronary blood flow and to test its ability to detect small changes in blood flow that may accompany pharmacologic intervention. High-frequency (5 MHz) transthoracic echocardiography was performed on the distal segment of the left anterior descending coronary artery of 32 consecutive patients (23 men and nine women; mean age 60 +/- 10 years) before and after the administration of 0.4 mg sublingual nitroglycerin. The results were compared with those of 10 patients (eight men and two women; mean age 59 +/- 6 years) in whom the ungrafted left internal mammary artery was studied. Doppler velocity profiles of the left anterior descending coronary artery were detected in 18 (56%) of the 32 Study patients. Left anterior descending coronary artery diameter and blood flow were measured in 14 patients (44%). There was no significant difference in blood flow between the left anterior descending artery (74 +/- 35 ml/min) and the internal mammary artery (52 +/- 25 ml/min). After administration of nitroglycerin, there was a 24% decrease in coronary blood flow from 74 +/- 35 ml/min to 56 +/- 30 ml/m...Continue Reading

References

Aug 1, 1992·Journal of the American College of Cardiology·J SegalR Siegel
Sep 1, 1988·Progress in Cardiovascular Diseases·C W WhiteM L Marcus
Sep 1, 1988·Journal of Clinical Ultrasound : JCU·K MiyatakeY Nimura
Mar 1, 1988·Journal of the American College of Cardiology·P S DouglasN Reichek
Apr 1, 1985·The American Journal of Cardiology·P J Block, R L Popp
Dec 1, 1981·Circulation·R L Feldman, C R Conti
Apr 1, 1982·Circulation·L D RinkJ E Marshall
Jan 1, 1993·American Heart Journal·T InoueY Takabatake
May 20, 1993·The American Journal of Cardiology·C W White
May 20, 1993·The American Journal of Cardiology·E O OfiliM J Kern

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Citations

Mar 2, 2010·Surgical and Radiologic Anatomy : SRA·Kevin N ChristensenNirusha Lachman
May 2, 2003·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Reidar WinterRonnie Willenheimer
Apr 3, 2007·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Wendy S TzouJames H Stein
Jun 10, 2006·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Dae-Won SohnYun-Shik Choi
Jul 10, 1999·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·D J Hildick-Smith, L M Shapiro
Mar 6, 1998·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·J J Crowley, L M Shapiro
Dec 6, 2003·American Journal of Physiology. Heart and Circulatory Physiology·Tuomas O KiviniemiJaakko J Hartiala
May 21, 1998·Herz·M Elsner

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