PMID: 9187699Jun 1, 1997Paper

Transurethral collagen injection for treatment of postprostatectomy urinary incontinence in men

Urology
T L GrieblingR D Williams

Abstract

Transurethral injection of glutaraldehyde cross-linked bovine collagen has recently been advocated as a potentially useful treatment modality for management of urinary incontinence. The reported clinical experience with urethral collagen injection in adult males has been limited. This study summarizes the current literature and reviews the clinical results of collagen injection in a group of 25 men with incontinence after either transurethral or radical prostatectomy. The overall results in this series were disappointing. Only 2 patients (8%) achieved significant improvement with this treatment. Eight patients (32%) experienced minimal improvement in symptoms, and 15 (60%) remained incontinent with no improvement in symptoms after collagen injection. The number of injection procedures and volume of collagen material implanted did not correlate with clinical outcome. Five patients (20%) have subsequently required placement of an artificial urinary sphincter to control their incontinence. We conclude that transurethral injection of glutaraldehyde cross-linked bovine collagen has a limited role in the management of urinary incontinence in adult men after prostatectomy.

References

Dec 1, 1992·The Journal of Urology·S HerschornD J Steele
Jan 1, 1992·British Journal of Urology·H KieswetterJ Flamm
Jan 1, 1992·British Journal of Urology·V A Politano
Dec 1, 1991·British Journal of Urology·S D Eckford, P Abrams
Feb 1, 1974·The Journal of Urology·V A PolitanoC M Lynne
Jan 1, 1996·The Journal of Urology·S R AboseifE J McGuire
Apr 1, 1994·Urology·E J McGuire, R A Appell
Jan 1, 1993·European Urology·M VandenbosscheC C Schulman

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Citations

Oct 1, 2011·Current Urology Reports·Dominic LeeRun Wang
Oct 8, 1999·Urology·R D CespedesE J McGuire
Mar 23, 1999·The Urologic Clinics of North America·R T Kershen, A Atala
Apr 29, 1998·The Journal of Urology·A J SchaefferT A Stamey
Dec 17, 1998·International Journal of Urology : Official Journal of the Japanese Urological Association·Y HommaK Hayashi
Apr 1, 2007·Indian Journal of Urology : IJU : Journal of the Urological Society of India·Ajay K Singla
Mar 22, 2000·Current Opinion in Urology·C C Carson
Oct 13, 2006·Current Opinion in Urology·S A Macdiarmid
Sep 21, 2006·International Journal of Urology : Official Journal of the Japanese Urological Association·Rahmi Onur, Ajay Singla
Dec 22, 2009·Neurourology and Urodynamics·Sender HerschornUNKNOWN Committee of the International Consultation on Incontinence
Nov 24, 1999·The Journal of Urology·J Q ClemensA J Schaeffer
Jul 25, 2006·Expert Opinion on Pharmacotherapy·Petros Perimenis, Konstantinos Giannitsas
Mar 22, 2014·Korean journal of urology·Sin Woo LeeKyu-Sung Lee
Oct 21, 2017·Neurourology and Urodynamics·Julio T Chong, Vannita Simma-Chiang
May 24, 2001·The Journal of Urology·J M GuysA Hautier
Apr 12, 2005·The Journal of Urology·Erik P CastleRobert G Ferrigni
May 9, 2001·The Journal of Urology·W KassoufJ Corcos
Jan 11, 2019·BioMed Research International·Janneke I M van UhmErik B Cornel
Feb 4, 2003·Archives of Pathology & Laboratory Medicine·Denis M McCarthyWilliam H Westra

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