PMID: 7518982Jul 1, 1994Paper

Transurethral microwave thermotherapy (TUMT) in benign prostatic hyperplasia: placebo versus TUMT

Urology
J J de la RosetteF F Debruyne

Abstract

A prospective, randomized placebo-controlled study was designed to exclude a placebo response in transurethral microwave thermotherapy (TUMT). During a sham procedure, the microwave applicator was installed in the urethra as in the real TUMT treatment and a complete procedure was simulated by the microwave delivery system (Prostatron). Any patient who entered this study had the option to request a second real TUMT treatment if, 3 months after the initial procedure, his condition had not improved. A total of 48 patients were available for evaluation at 3 months and 28 at 6 months. The TUMT group had an average decrease of 7.3 points (from 13.2 to 5.9) in the Madsen symptom score, an average increase in flowrate of 3.4 mL/s (9.6 to 13.0), and an increase in voiding percentage of 9.6% (81.7 to 91.3). All improvements were statistically significant. In the sham group, the average Madsen score decreased from 12.1 to 8.2 points, the average flowrate decreased from 9.7 to 9.5 mL/s, and the voiding percentage increased from 80.8% to 84.3%. Only the change in symptom score was significant. In both groups, observations at the 3-month follow-up were similar to those after 6 and 12 months. Patients who had TUMT after sham treatment showed ...Continue Reading

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Citations

Nov 1, 1995·The Journal of Urology·K M Slawin
Apr 2, 1998·British Journal of Urology·J M GlassR O Witherow
Jan 10, 2003·BJU International·B DjavanM Marberger
Nov 18, 2000·Journal of Endourology·M P LagunaF M Debruyne
Nov 18, 2000·Journal of Endourology·M J de WildtT Eliasson
Nov 18, 2000·Journal of Endourology·W J Lynch, S F Graber
Jul 1, 1995·International Journal of Urology : Official Journal of the Japanese Urological Association·A TeraiO Yoshida
Nov 1, 1996·International Journal of Urology : Official Journal of the Japanese Urological Association·Y KuritaK Kawabe
Oct 13, 2006·Current Opinion in Urology·P J Gilling, M R Fraundorfer
Mar 1, 1997·The Journal of Urology·D S BenjaminS C Stewart
Feb 1, 1997·The Journal of Urology·J J de la RosetteF M Debruyne
Apr 1, 1996·Scandinavian Journal of Urology and Nephrology·T U EliassonJ E Damber

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