Transvaginal color Doppler sonographic assessment of uterus and ovaries in postmenopausal women: the effect of local estrogen treatment

European Journal of Obstetrics, Gynecology, and Reproductive Biology
Jittima ManonaiUrusa Theppisai

Abstract

The objective was to evaluate the effect of local estrogen treatment on the uterus and ovaries using transvaginal color Doppler sonography. A 12-week randomized open-label study of postmenopausal women taking local estrogen treatment and controls was conducted. The study group was treated with either a 25-mum estradiol vaginal tablet or 1g of conjugated estrogen cream intravaginally each day for 2 weeks followed by twice a week for 10 weeks. The control group did not receive any type of hormone replacement therapy. All women underwent transvaginal ultrasonography and color Doppler imaging of the uterine arteries both before starting local estrogen treatment and after treatment. The uterine volume, ovarian volume, endometrial thickness, and uterine arterial blood flow of the two groups were evaluated. Statistical analysis was performed using paired and unpaired Student's t-test. A p value of <0.05 was considered statistically significant. Of the 53 postmenopausal women recruited to this study, 26 women received local estrogen treatment for treatment of urogenital symptoms and 27 untreated women constituted the control group. The mean age was 54.85+/-5.51 years. The uterine and ovarian volumes were not significantly different bef...Continue Reading

References

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Citations

Jul 16, 2009·Menopause : the Journal of the North American Menopause Society·David F Archer
Nov 26, 2008·Vojnosanitetski pregled. Military-medical and pharmaceutical review·Ranko KutlesićMilan Stefanović
Jan 2, 2009·Climacteric : the Journal of the International Menopause Society·O Al-Baghdadi, A A A Ewies
Jan 15, 2013·Maturitas·Sonia M Rolim Rosa LimaTsutomu Aoki
Jan 9, 2020·Menopause : the Journal of the North American Menopause Society·Carolyn J CrandallNanette Santoro
Sep 9, 2010·The Cochrane Database of Systematic Reviews·Sharif I IsmailSuzanne Hagen

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