Traumatic neuromas of the penis: a clinical, histopathological and immunohistochemical study of 17 cases

Journal of Cutaneous Pathology
Eduardo SalcedoHideko Kamino

Abstract

We present 17 penile traumatic neuromas. The mean patient age at presentation was 38 years (range 23-59 years). The most common site involved was the penile shaft. The lesions ranged from 1 to 7 mm in greatest dimension. The clinical diagnosis in all cases included condyloma acuminatum. In all cases, a history of trauma because of prior biopsy and/or circumcision was found. Histologically, all lesions showed similar features consisting of an increased number of dermal nerve bundles embedded within a fibrous stroma. Often, single or multiple Meissner corpuscle-like structures were noted in the papillary dermis. Our study suggests that circumcision or other forms of trauma to the skin of the penis likely plays an important role in the pathogenesis and clinical presentation of this peculiar neural neoplasm. We call attention to this entity because it is often clinically misdiagnosed as condyloma acuminatum.

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Citations

Nov 26, 2014·The Journal of Sexual Medicine·Jasmine AbdulcadirLale Say
Dec 8, 2011·The Journal of Sexual Medicine·Jasmine AbdulcadirAnne-Thérèse Vlastos
Jun 15, 2010·Journal of the American Academy of Dermatology·Rashid M RashidValencia Thomas
Dec 21, 2013·The Journal of Dermatology·Jiwon GyeMyunghwa Kim
Jul 2, 2015·Anais Brasileiros De Dermatologia·Thaís Abrão CardosoJosé Roberto Pereira Pegas
Jun 13, 2018·The American Journal of Dermatopathology·Alejandro Lobato-BerezoMaría Teresa Fernández-Figueras
May 25, 2020·Journal of Cutaneous Pathology·Titilola SodeGregory A Hosler
Feb 10, 2017·Reproductive Health·Jasmine AbdulcadirPatrick Petignat
Aug 31, 2019·Case Reports in Obstetrics and Gynecology·Dani ZoorobSonyoung Seo-Patel

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