Treadmill Training with Cues and Feedback Improves Gait in People with More Advanced Parkinson's Disease

Journal of Parkinson's Disease
Valeria StuderGiuseppe Frazzitta

Abstract

Gait disturbances in Parkinson's disease (PD) are highly disabling and poorly responsive to drugs, especially in advanced stages. While the efficacy of a treadmill training based on external feedback and cues (treadmill-plus) on gait disturbances in early PD stages is demonstrated, no definitive evidence exists about advanced stages. We aimed to evaluate the feasibility and the effects of a treadmill-plus training on gait disturbances in advanced PD. Two hundred and six PD patients from medium to more advanced Hoehn & Yahr stage (stage 2, n = 79, stage 3 n = 74, and stage 4 = 53) who underwent a 4-week treadmill-plus training, were retrospectively identified. All patients were able to walk on a treadmill for one minute at 1.5 km/h, without support. Feasibility was evaluated by measuring safety, adverse events, and attrition rate. The effects of treatment were evaluated by assessing, both at enrolment and at the end of treatment, the on-land, self-paced 6-minute Walking Test (6MWT) and the gait parameters obtained from the treadmill during a 1.5 km/h trial. All patients completed the treadmill-plus training and no adverse events were recorded, even among more disabled patients. After training, we observed a significant improveme...Continue Reading

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