Treated hydrocephalus in individuals with myelomeningocele in the National Spina Bifida Patient Registry

Journal of Neurosurgery. Pediatrics
Irene KimBrandon G Rocque

Abstract

OBJECTIVEAlthough the majority of patients with myelomeningocele have hydrocephalus, reported rates of hydrocephalus treatment vary widely. The purpose of this study was to determine the rate of surgical treatment for hydrocephalus in patients with myelomeningocele in the National Spina Bifida Patient Registry (NSBPR). In addition, the authors explored the variation in shunting rates across NSBPR institutions, examined the relationship between hydrocephalus, and the functional lesion level of the myelomeningocele, and evaluated for temporal trends in rates of treated hydrocephalus.METHODSThe authors queried the NSBPR to identify all patients with myelomeningoceles. Individuals were identified as having been treated for hydrocephalus if they had undergone at least 1 hydrocephalus-related operation. For each participating NSBPR institution, the authors calculated the proportion of patients with treated hydrocephalus who were enrolled at that site. Logistic regression was performed to analyze the relationship between hydrocephalus and the functional lesion level of the myelomeningocele and to compare the rate of treated hydrocephalus in children born before 2005 with those born in 2005 or later.RESULTSA total of 4448 patients with...Continue Reading

References

Jan 1, 1979·Child's Brain·S C Stein, L Schut
Oct 2, 2003·American Journal of Obstetrics and Gynecology·Mark P JohnsonN Scott Adzick
May 2, 2008·Journal of Neurosurgery. Pediatrics·Aabir ChakrabortyDominic Thompson
Mar 28, 2009·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Robin M BowmanDavid G McLone
Feb 11, 2011·The New England Journal of Medicine·N Scott AdzickUNKNOWN MOMS Investigators
Jan 1, 2009·Journal of Pediatric Neurosciences·Suresh Sankhla, G M Khan
Nov 6, 2012·Birth Defects Research. Part A, Clinical and Molecular Teratology·Judy K ThibadeauMichael S Schechter
Jun 1, 2014·Journal of Neurosurgery. Pediatrics·Blake C PhillipsGregory W Albert
Dec 3, 2014·The Journal of Pediatrics·Kathleen J SawinUNKNOWN NSBPR Coordinating Committee
Sep 16, 2015·Journal of Neurosurgery. Pediatrics·Noel TulipanUNKNOWN for the MOMS Investigators
Dec 29, 2016·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Nicholas M B LaskayBrandon G Rocque

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Citations

Oct 24, 2019·Birth Defects Research·Renata H BenjaminA J Agopian
Oct 2, 2019·Neurosurgical Focus·Jochem K H SpoorTjeerd H R de Jong
Aug 11, 2019·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Francesco T ManganoWeihong Yuan

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