Abstract
Transfusion therapy is frequently used in the treatment of sickle cell disease and its complications, but its efficacy has not been well proven. Red cell transfusions are well established for the acute treatment of cerebrovascular accidents and for the prevention of their recurrence. Acute chest syndrome with respiratory insufficiency is also an established indication for transfusion, especially in children. The use of red cell transfusions, especially chronic transfusions, in the treatment of sickle cell disease should be initiated only after serious consideration of the clinical setting and possible adverse effects. Both risks and benefits should be discussed with the patient, and that discussion should be documented.
References
Mar 19, 1992·Nature·D LookerG Fermi
Aug 6, 1992·The New England Journal of Medicine·R Y Dodd
Jun 7, 1990·The New England Journal of Medicine·S Charache
Jan 1, 1987·Transfusion·D R AmbrusoT Hays
Dec 1, 1967·Annals of Internal Medicine·S Charache, D L Page
Jun 1, 1984·The Journal of Pediatrics·A R CohenE Schwartz
Jun 1, 1984·Archives of Surgery·K WaxmanG R Mason
Jan 1, 1982·Transfusion·K JanJ A Smith
Feb 1, 1980·The Journal of Pediatrics·J WilimasE Thompson
Dec 28, 1995·The New England Journal of Medicine·E M LackritzL R Petersen
Jul 1, 1994·Transfusion·H R TahhanJ D Christie
Jul 1, 1993·Transfusion·R S EisenstaedtT Derstine
Apr 1, 1993·Transfusion Medicine Reviews·S Dzik
Sep 1, 1957·Vox Sanguinis·R PAYNE
Sep 1, 1961·Acta Paediatrica·H MEGASB CONSTANTINIDES
May 1, 1964·American Journal of Diseases of Children·E CHARNEY, G MILLER
Citations
Jul 26, 2000·Therapeutic Apheresis : Official Journal of the International Society for Apheresis and the Japanese Society for Apheresis·L J McCarthyC F Danielson
Jul 14, 2001·Radiographics : a Review Publication of the Radiological Society of North America, Inc·G J LonerganS L Abbondanzo
Jan 7, 2010·The American Journal of the Medical Sciences·Leslie P Scheunemann, Kenneth I Ataga
Feb 11, 1999·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·D R Lawrenz
Feb 16, 2019·Transfusion·Athira UnnikrishnanMolly W Mandernach
Jan 29, 2000·Postgraduate Medicine·S H YaleT Guthrie