Treating Different Diseases With the Same Method-A Traditional Chinese Medicine Concept Analyzed for Its Biological Basis

Frontiers in Pharmacology
Xing ZhaiXiaohan Pang

Abstract

The fundamental theory of traditional Chinese medicine (TCM) implies that when different diseases have the same pathogen, the syndromes of these individual diseases will be the same. "Treating different diseases with the same method" is a TCM principle suggesting that when different diseases have similar pathological changes during different stages of their development, the same method of treatment can be applied. Our study aims to analyze the concept "treating different diseases with the same method" from a molecular perspective, in order to clarify its biological basis and to objectively standardize future TCM syndrome research. The TCM syndromes Qi deficiency and blood stasis have similar pathogenesis in relation to coronary heart disease (CHD) and stroke. We aim to use big data technology and complex network theory to mine the genes specifically relevant to these TCM syndromes. This study aims to explore the correlation between the biological indicators of CHD and stroke from a scientific perspective. Mining the relevant neuroendocrine-immune (NEI) genes by means of gene entity recognition, complex network construction, network integration, and decomposition to categorize relevant syndrome terms and establish a digital dict...Continue Reading

References

Mar 1, 1987·Nature·J W Lichtman, P H Taghert
Jan 1, 1973·International Archives of Allergy and Applied Immunology·K Isaković, B D Janković
Jan 31, 2004·Bioinformatics·Minghua DengTing Chen
Jun 30, 2006·Biochemical and Biophysical Research Communications·Atsushi HosuiNorio Hayashi
Dec 31, 2008·Nature Reviews. Immunology·Jochen HuehnAlf Hamann
May 24, 2012·Stroke; a Journal of Cerebral Circulation·Adviye ErgulSusan C Fagan
Oct 10, 2013·QJM : Monthly Journal of the Association of Physicians·S S DingY Xu
Mar 21, 2015·Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology·Rui-Xing WangMo-Jun Lin
Oct 27, 2018·Nucleic Acids Research·Hai-Yu XuLu-Qi Huang

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Citations

Oct 10, 2021·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Shan-Qiang ZhangJi-Cheng Li

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Software Mentioned

SMIL
Symmap
Jieba
TCMIP
Genclip
Pajek
WOS
Mesh
STRING

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