PMID: 9192537Apr 1, 1997Paper

Treatment algorithms in child psychopharmacology research

Journal of Child and Adolescent Psychopharmacology
B Vitiello

Abstract

Clinical trials in child psychiatry research have increased in complexity. Several factors have contributed to this change, including the need to compare multiple therapies, to re-create clinically relevant situations in research, to standardize treatment approaches, to account for the impact of comorbidity, to respond to the needs of individual patients, and to optimize treatment accordingly. To preserve the clinical and internal validity of the experimental interventions vis-à-vis their increasing complexity, researchers have started developing treatment algorithms. These deductive systems for handling data allow us to standardize and incorporate clinical judgment into study designs through the adoption of a stepwise decision making process. Treatment algorithms are different from treatment guidelines. Guidelines are general recommendations that apply to groups of patients with certain characteristics; they are not fully detailed and are created with the expectation that clinical judgment will be applied in individual cases. Algorithms are patient specific, are intended to capture all the relevant details of the clinical situation, and require minimal clinical judgment for their clinical application; they are designed to mini...Continue Reading

References

Jan 1, 1997·Psychopharmacology·B Givens

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Citations

Oct 24, 1998·Journal of the American Academy of Child and Adolescent Psychiatry
May 7, 1999·Journal of the American Academy of Child and Adolescent Psychiatry·P S JensenL B Burke
Nov 24, 1999·Journal of the American Academy of Child and Adolescent Psychiatry·J L Woolston

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