Treatment and dosimetric advantages between VMAT, IMRT, and helical tomotherapy in prostate cancer

Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists
Chiao-Ling TsaiJason Chia-Hsien Cheng

Abstract

We investigated the possible treatment and dosimetric advantage of volumetric modulated arc therapy (VMAT) over step-and-shoot intensity-modulated radiation therapy (step-and-hhoot IMRT) and helical tomotherapy (HT). Twelve prostate cancer patients undergoing VMAT to the prostate were included. Three treatment plans (VMAT, step-and-shoot IMRT, HT) were generated for each patient. The doses to clinical target volume and 95% of planning target volume were both ≥ 78 Gy. Target coverage, conformity index, dose to rectum/bladder, monitor units (MU), treatment time, equivalent uniform dose (EUD), normal tissue complication probability (NTCP) of targets, and rectum/bladder were compared between techniques. HT provided superior conformity and significantly less rectal volume exposed to 65 Gy and 40 Gy, as well as EUD/NTCP of rectum than step-and-shoot IMRT, whereas VMAT had a slight dosimetric advantage over step-and-shoot IMRT. Notably, significantly lower MUs were needed for VMAT (309.7 ± 35.4) and step-and-shoot IMRT (336.1 ± 16.8) than for HT (3368 ± 638.7) (p < 0.001). The treatment time (minutes) was significantly shorter for VMAT (2.6 ± 0.5) than step-and-shoot IMRT (3.8 ± 0.3) and HT (3.8 ± 0.6) (p < 0.001). Dose verification o...Continue Reading

References

May 15, 1991·International Journal of Radiation Oncology, Biology, Physics·C BurmanM Goitein
Jun 1, 1997·International Journal of Radiation Oncology, Biology, Physics·D FollowillA Boyer
Apr 16, 1998·International Journal of Radiation Oncology, Biology, Physics·D A LowJ A Purdy
Nov 13, 2001·International Journal of Radiation Oncology, Biology, Physics·UNKNOWN Intensity Modulated Radiation Therapy Collaborative Working Group
Jan 5, 2002·International Journal of Radiation Oncology, Biology, Physics·Qiuwen WuRupert Schmidt-Ullrich
Jul 20, 2002·International Journal of Radiation Oncology, Biology, Physics·Alan PollackIsaac Rosen
Jul 20, 2002·International Journal of Radiation Oncology, Biology, Physics·Michael J ZelefskySteven A Leibel
Mar 8, 2005·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Bin S TehE Brian Butler
May 2, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Stephanie T H PeetersJoos V Lebesque
Sep 20, 2006·Acta Oncologica·Marika EnmarkHåkan Nyström
Jul 28, 2007·Medical Physics·Ellen E Wilcox, George M Daskalov
Dec 18, 2007·Seminars in Radiation Oncology·Oren CahlonMichael J Zelefsky
Jan 12, 2008·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Florian SterzingKlaus Herfarth
Oct 16, 2008·Acta Oncologica·Flemming Kjaer-KristoffersenStine Korreman
Jun 23, 2009·International Journal of Radiation Oncology, Biology, Physics·Pengpeng ZhangGig Mageras
Aug 14, 2009·Medical Physics·Juan Pardo-Montero, John D Fenwick
Sep 17, 2009·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Chiao-Ling TsaiJason Chia-Hsien Cheng
Nov 26, 2009·Medical Physics·Eduard SchreibmannTim Fox

❮ Previous
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Citations

Dec 13, 2012·Medical Physics·Juan Pardo-Montero, John D Fenwick
Nov 27, 2014·Radiation Oncology·Yvonne DziermaChristian Rübe
Jan 13, 2012·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Szu-Huai LuChun-Wei Wang
Oct 19, 2013·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·C-Y LinC-S Lin
Jul 12, 2014·Practical Radiation Oncology·Peng DongKe Sheng
Nov 29, 2011·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Giovanni FavaMarco Schwarz
Sep 15, 2016·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Cem OnalEsma Efe
Apr 9, 2014·Journal of Applied Clinical Medical Physics·Jung-in KimSung-Joon Ye
Aug 27, 2014·Journal of Evidence-based Medicine·Zong Xia YangUNKNOWN Rapid Health Technology Assessment Working Group of Chinese Evidence-Based Medicine Centre
Jun 1, 2014·Journal of Medical Radiation Sciences·Craig A ElithHelen M Warren-Forward
May 23, 2019·International Journal of Urology : Official Journal of the Japanese Urological Association·Kazuo HatanoKoichi Konoeda
Dec 25, 2019·Radiation Oncology·Jong Min ParkSo-Yeon Park
Jun 14, 2019·Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology·Elona CekaniRaul Matute
Jun 14, 2019·Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology·Łukasz TrembeckiAdam Maciejczyk

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