Treatment and prognosis of oral mucosal melanoma

Oral Oncology
Chuan-Zheng SunMing Song

Abstract

To evaluate the treatment and prognosis of oral mucosal melanoma (OMM) and provide basic data for clinical treatment. Retrospective analysis of clinicopathological data on OMM from January 1976 to December 2005. Survival analysis was performed and Kaplan-Meier analysis was used to compare the effects of clinicopathological factors on survival using SPSS 18.0 software. A Cox model was applied for multivariate analysis. The 3-year and 5-year overall survival (OS) rates of 51 cases of OMM were 35.0% and 20.7%, respectively. Lymph node metastatic sites were predominantly at levels Ib-III (29/31, 93.5%). Patients of age ≥55 years and size ≥4 cm had a lower survival rate than those of aged <55 years and size <4 cm. The 3-year OS and 5-year OS of patients who underwent surgery combined with biotherapy or biochemotherapy (70.1% and 58.4%, respectively) were significantly higher than that of patients who underwent other therapeutic regimens (including surgery, chemotherapy, surgery combined with radiotherapy or surgery combined with chemotherapy) (25.0% and 12.5%, respectively). Multivariate analysis showed that surgery combined with biotherapy or biochemotherapy and neck dissection were effective treatments for OMM. Patients aged ≥55 y...Continue Reading

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Citations

Nov 13, 2013·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Tobias EttlMartin Gosau
Jul 31, 2014·Journal of the American Veterinary Medical Association·Sarah E BostonPaolo Buracco
Apr 4, 2016·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Ioannis ChatzistefanouKonstantinos Antoniades
Aug 12, 2015·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Faruk Kadri BakkalUtku Aydil
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Oct 16, 2016·Radiation Oncology·Gaber PlavcPrimož Strojan
Nov 14, 2014·Cancer Informatics·Nancy Lan Guo, Ying-Wooi Wan
Jun 4, 2019·BMJ Case Reports·Madhusudan AstekarSantosh Gupta
Apr 4, 2021·International Journal of Environmental Research and Public Health·Stefano BondiSilvio Abati
Jun 6, 2021·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Ximena MimicaFelipe Contreras
Aug 25, 2021·European Journal of Dentistry·Kritsasith WarinNutdanai Pattanajakr

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