Treatment default and death among tuberculosis patients in Hunan, China

Scandinavian Journal of Infectious Diseases
Benjamin AbuakuXin Huang

Abstract

We used the 2005 and 2006 national surveillance data to elucidate some of the risk factors for treatment default and death among tuberculosis (TB) patients in Hunan, China. Risk of default was higher in males (odds ratio (OR) 1.25; 95% confidence interval (CI) 1.08, 1.44); lowest in patients aged 15-24 y (OR 0.60; 95% CI 0.49, 0.75), and generally increased with increasing age; lower in patients living in cities with per capita gross domestic product (GDP) of less than 1000 US$ (OR 0.60, 95% CI 0.49, 0.72), and increased with increasing per capita GDP of city of residence; and higher in patients with previously treated smear-positive pulmonary TB (diagnostic category II according to the World Health Organization definition; OR 1.99; 95% CI 1.22, 3.23). Risk of death was lowest in patients aged 15-24 y (OR 0.07; 95% CI 0.05, 0.10), and increased with increasing age; lower in new cases (OR 0.50; 95% CI 0.33, 0.76); and highest in patients who treated themselves (OR 3.47; 95% CI 1.27, 9.46). We conclude that male TB patients, elderly TB patients, patients resident in cities with higher per capita GDP, and patients receiving category II treatment need special attention to reduce TB treatment default in the province. Furthermore, el...Continue Reading

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Citations

Mar 6, 2012·Transactions of the Royal Society of Tropical Medicine and Hygiene·Yung-Feng YenChung-Yeh Deng
Dec 7, 2014·Asian Pacific Journal of Tropical Medicine·Isaac AlobuKingsley N Ukwaja
Mar 27, 2015·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Joel NeginBen J Marais
Aug 11, 2020·Canadian Respiratory Journal : Journal of the Canadian Thoracic Society·Yunli ZhangWenen Liu
Aug 8, 2020·Archives of public health = Archives belges de santé publique·Daniel Bekele KetemaMehari Woldemariam Merid

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