Treatment for diabetic foot ulcers complicated by major cardiac events

Canadian Journal of Diabetes
Shih-Yuan HungChih-Ching Wang

Abstract

Diabetic foot ulcer (DFU) is a major complication in patients with diabetes mellitus and the leading cause of non-traumatic amputation in adults. Patients with DFU are usually fragile due to chronic diabetic comorbidities; therefore, tedious debridement and intervention procedures may not be well tolerated in patients with DFU. This study aimed to identify a casual relationship between in-hospital complications and treatment for limb-threatening DFUs. From 2009 to 2011, 1130 consecutive patients who were admitted to the Diabetic Foot Care Center in Chang Gung Medical Center were surveyed. Rates of in-hospital mortality or events that lead to transfer to the intensive care unit (ICU) for various severe complications were retrospectively analyzed. Forty-seven patients (4.2%) experienced in-hospital complications (28 patients died). Major adverse cardiac events (MACE) (n=21, 44.7%) were the most common complications, followed by nosocomial infection (n=18, 38.3%). Previous myocardial infarction was a risk factor for MACE. The presentation of MACE was fulminant (eg, acute pulmonary edema, cardiogenic shock,cardiac arrest), and occurred within 10 days of admission or within 10 days following a major procedure in most cases. ST-T seg...Continue Reading

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Citations

Jun 17, 2015·Journal of Wound Care·Bahle Nteleki, Mazizi Njokweni
Nov 22, 2018·The International Journal of Lower Extremity Wounds·Mohita SinghNeal R Barshes
Aug 22, 2021·Journal of Diabetes Investigation·Shih-Yuan HungYu-Yao Huang

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