PMID: 8950729Jan 1, 1996Paper

Treatment for patients with recurrent abortion with positive antiphospholipid antibodies using a traditional Chinese herbal medicine

Journal of Perinatal Medicine
Koichi TakakuwaK Tanaka

Abstract

Twelve patients with recurrent abortion who had shown positive antiphospholipid antibodies were treated through the administration of a Japanese modified traditional Chinese herbal medicine Sairei-To (Chan ling-Tang) The patients had experienced a total of 27 spontaneous abortions in their previous pregnancies and had no other pregnancy history except for one patient. The patients were treated with 9.0 g of Sairei-To per day before their next pregnancy. The positive value of antiphospholipid antibodies returned to negative in 9 patients out of 12 patients through the treatment. Out of 12 patients, in 10 patients, their new pregnancy continued uneventfully and delivered an offspring (Success rate: 83.3%). Thus, the current treatment was considered to be an effective therapy for patients with recurrent abortion who were found to be positive for antiphospholipid antibodies.

References

Sep 1, 1992·Human Reproduction·J BódisM Gross
May 1, 1991·American Journal of Obstetrics and Gynecology·A el-RoeiyN Gleicher
Jul 1, 1988·American Journal of Obstetrics and Gynecology·N Gleicher, A el-Roeiy
Nov 21, 1985·The New England Journal of Medicine·D W BranchE Hershgold

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Citations

Apr 13, 2002·BJOG : an International Journal of Obstetrics and Gynaecology·E Ernst
Aug 30, 2006·American Journal of Reproductive Immunology : AJRI·Koichi TakakuwaKenichi Tanaka
Jun 4, 2014·The Journal of Obstetrics and Gynaecology Research·Taro NonakaKoichi Takakuwa
Nov 14, 1997·Obstetrical & Gynecological Survey·R A Chez, W B Jonas

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Antiphospholipid Syndrome

Antiphospholipid syndrome or antiphospholipid antibody syndrome (APS or APLS), is an autoimmune, hypercoagulable state caused by the presence of antibodies directed against phospholipids.