Treatment for ventricular arrhythmias in the absence of structural heart disease: from guidelines to clinical practice

Terapevticheskiĭ arkhiv
D A TsaregorodtsevA V Nedostup

Abstract

To determine criteria for choosing management tactics in patients with ventricular arrhythmias (VA) in the absence of structural heart disease from the point of view of physicians and patients in clinical practice and to compare the immediate results of antiarrhythmic drug therapy (ADT) and radiofrequency ablation (RFA) with the trends in arrhythmic syndrome in the non-treatment group. Examinations were made in 90 patients (23 men and 67 women) (mean age, 44 (31; 57) years) with VA in the absence of structural heart disease. Preference was given to RFA (n = 32 (36%)), ADT (n = 37 (41%)), and follow-up tactics (n = 21 (23%)). At baseline and 1 month, Holter ECG monitoring was done; quality of life (QOL) was assessed; and anxiety and depression levels were detected using the SF-36 and HADS questionnaires. In addition, 71 physicians were surveyed about their preferences to the treatment of VA in individuals without structural heart disease. In the total group of patients, VA was unambiguously accompanied by the symptoms only in 47%. The signs of anxiety and depression were identified in 41 and 14% of cases, respectively. The efficiency of RFA was comparable to that of ADT (p > 0.1): a positive antiarrhythmic effect was observed in...Continue Reading

References

Sep 11, 2007·Health and Quality of Life Outcomes·Sepideh S FarivarRon D Hays
Jul 9, 2009·Journal of Cardiovascular Medicine·Nicola BottoniCarlo Menozzi
Jun 28, 2012·European Journal of Heart Failure·Kenji KurokiKazutaka Aonuma
Oct 26, 2013·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Li ZhongYong-Mei Cha
May 16, 2015·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Kyoung-Min ParkYoung Keun On

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