Treatment for Word Retrieval in Semantic and Logopenic Variants of Primary Progressive Aphasia: Immediate and Long-Term Outcomes

Journal of Speech, Language, and Hearing Research : JSLHR
Maya L HenryMaria Luisa Gorno-Tempini

Abstract

Purpose Recent studies confirm the utility of speech-language intervention in primary progressive aphasia (PPA); however, long-term outcomes, ideal dosage parameters, and relative benefits of intervention across clinical variants warrant additional investigation. The purpose of this study was to determine whether naming treatment affords significant, lasting, and generalized improvement for individuals with semantic and logopenic PPA and whether dosage manipulations significantly affect treatment outcomes. Method Eighteen individuals with PPA (9 semantic and 9 logopenic variant) underwent lexical retrieval treatment designed to leverage spared cognitive-linguistic domains and develop self-cueing strategies to promote naming. One group (n = 10) underwent once-weekly treatment sessions, and the other group (n = 8) received the same treatment with 2 sessions per week and an additional "booster" treatment phase at 3 months post-treatment. Performance on trained and untrained targets/tasks was measured immediately after treatment and at 3, 6, and 12 months post-treatment. Results Outcomes from the full cohort of individuals with PPA showed significantly improved naming of trained items immediately post-treatment and at all follow-up...Continue Reading

References

Nov 1, 1975·Journal of Psychiatric Research·M F FolsteinP R McHugh
Dec 1, 1987·The British Journal of Disorders of Communication·C Bruce, D Howard
Feb 1, 1996·Annals of Neurology·R S TurnerM Grossman
Dec 17, 1997·Brain and Language·C Westbury, D Bub
Jul 7, 2001·Stroke; a Journal of Cerebral Circulation·F PulvermüllerE Taub
May 7, 2002·Neuropsychologia·Julie S Snowden, David Neary
Aug 21, 2003·Journal of Communication Disorders·Michelle S BourgeoisMichael Rovine
Dec 11, 2003·Cognitive and Behavioral Neurology : Official Journal of the Society for Behavioral and Cognitive Neurology·Joel H KramerBruce L Miller
Feb 12, 2004·Topics in Stroke Rehabilitation·Lynn M Maher, Anastasia M Raymer
Mar 3, 2004·Annals of Neurology·Maria Luisa Gorno-TempiniBruce L Miller
Sep 2, 2004·American Journal of Speech-language Pathology·Mary Boyle
Apr 26, 2005·Neurocase·Murray Grossman, Sharon Ash
Mar 29, 2006·Applied Microbiology and Biotechnology·Michael Cunliffe, Michael A Kertesz
Jul 13, 2006·Neuropsychological Rehabilitation·Regina JokelCarol Leonard
Oct 27, 2006·Journal of the International Neuropsychological Society : JINS·Pélagie M Beeson, Heather Egnor
Dec 8, 2006·Neuropsychology Review·Pélagie M Beeson, Randall R Robey
Feb 28, 2007·Mental Retardation and Developmental Disabilities Research Reviews·Steven F WarrenPaul J Yoder
Oct 20, 2007·Lancet Neurology·John R Hodges, Karalyn Patterson
Dec 20, 2007·Alzheimer Disease and Associated Disorders·Jennifer M OgarMaria Luisa Gorno-Tempini
Jan 31, 2008·Journal of Speech, Language, and Hearing Research : JSLHR·Jeffrey A Kleim, Theresa A Jones
Jul 18, 2008·Neurology·M L Gorno-TempiniB L Miller
Oct 3, 2008·Brain : a Journal of Neurology·David S KnopmanNathaniel Mercaldo
Nov 11, 2008·Annals of Neurology·Gil D RabinoviciMaria Luisa Gorno-Tempini
Jun 9, 2009·Neuropsychological Rehabilitation·Regina JokelNicole D Anderson
Aug 15, 2009·NeuroImage·Jonathan D RohrerJason D Warren
Apr 3, 2010·Journal of Speech, Language, and Hearing Research : JSLHR·Pélagie M BeesonSteven Z Rapcsak
Apr 14, 2010·Archives of Neurology·Andrew KerteszPaul McMonagle
Jun 15, 2010·Brain : a Journal of Neurology·Stephen M WilsonMaria Luisa Gorno-Tempini
Jun 29, 2010·Neurobiology of Aging·Jonathan D RohrerJason D Warren
Sep 21, 2010·Current Opinion in Neurology·Maya L Henry, Maria Luisa Gorno-Tempini
Dec 17, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Stephen M WilsonMaria Luisa Gorno-Tempini
Feb 18, 2011·Neurology·M L Gorno-TempiniM Grossman
Jan 1, 2010·Journal of Alzheimer's Disease : JAD·George PengasPeter J Nestor
Jun 29, 2011·Journal of Molecular Neuroscience : MN·Pélagie M BeesonSteven Z Rapcsak
Jan 19, 2012·Neuropsychological Rehabilitation·Regina Jokel, Nicole D Anderson
Apr 25, 2012·Brain : a Journal of Neurology·M-Marsel MesulamSandra Weintraub
Jun 27, 2012·International Journal of Speech-language Pathology·Leora R Cherney
Aug 1, 2012·American Journal of Speech-language Pathology·Tammy HopperTracy Schooling
Aug 25, 2012·International Journal of Speech-language Pathology·Elise Baker
Nov 7, 2012·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Sharon A SavageJohn R Hodges

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Citations

Jul 31, 2019·Practical Neurology·Anna VolkmerJonathan D Rohrer
Sep 11, 2020·American Journal of Speech-language Pathology·Eduardo EuropaMaya L Henry
Oct 13, 2020·Alzheimer's & Dementia : Translational Research & Clinical Interventions·Keir X X YongSebastian J Crutch
Nov 13, 2020·Journal of Speech, Language, and Hearing Research : JSLHR·Maurice FlurieJamie Reilly
Jan 26, 2021·Frontiers in Human Neuroscience·Heather R DialMaya L Henry
Feb 6, 2021·Current Neurology and Neuroscience Reports·Justina RuksenaiteChris Jd Hardy
Mar 2, 2021·Expert Review of Neurotherapeutics·Cathleen Taylor-RubinLyndsey Nickels
Apr 20, 2021·American Journal of Speech-language Pathology·Diana PetroiKeith A Josephs
Apr 20, 2021·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Cathleen Taylor-RubinLyndsey Nickels
May 22, 2021·Journal of Speech, Language, and Hearing Research : JSLHR·Ashleigh DoubBrielle C Stark
Jul 17, 2021·Translational Neurodegeneration·Ilaria PagnoniRosa Manenti
Jul 28, 2021·American Journal of Speech-language Pathology·Kristin M SchafferMaya L Henry

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