Treatment history and association between allergic rhinitis symptoms and quality of life

Irish Journal of Medical Science
Marlene M SpethA R Sedaghat

Abstract

Recalcitrance of allergic rhinitis (AR) to medical management may be reflective of patient-specific impact of AR symptoms. To understand the relationship between AR symptoms and general health-related quality of life (QOL) or AR control, based on treatment status. Cross-sectional cohort study of 130 adult participants-65 using no allergy medications and 65 consistently using intranasal corticosteroid sprays (ICS) in the last 3 months-presenting with persistent AR. General health-related QOL was measured using the EuroQol 5-dimensional visual analog scale (EQ-5D VAS). Severity and control of AR symptoms were measured using the 22-item Sinonasal Outcome Test (SNOT-22) and the Rhinitis Control Assessment Test (RCAT), respectively. We compared associations between AR symptoms and general health-related QOL and AR control in patients presenting with persistent AR with and without ICS use. Severity of AR symptoms was similar between cohorts. In participants using no allergy medications, extranasal AR symptom severities were most dominantly associated with decreased EQ-5D VAS and RCAT score. In participants using ICS, only nasal symptom severities were associated with decreased EQ-5D VAS and RCAT scores. Consistently, only in particip...Continue Reading

References

Nov 2, 2004·The European Respiratory Journal·V Bauchau, S R Durham
Aug 18, 2006·Allergy and Asthma Proceedings·Michael S BlaissStuart Stoloff
Mar 30, 2007·Allergy and Asthma Proceedings·Robert A Nathan
Dec 6, 2007·Allergy·G W CanonicaJ C Virchow
Jul 31, 2008·The Journal of Allergy and Clinical Immunology·Dana V WallaceUNKNOWN Joint Council of Allergy, Asthma and Immunology
Dec 17, 2008·Archives of Otolaryngology--head & Neck Surgery·Nobuaki HirakiTeruo Shiomori
Apr 22, 2009·American Journal of Rhinology & Allergy·Melissa A PynnonenJeffrey E Terrell
Oct 22, 2009·Allergy and Asthma Proceedings·Amanda R SkonerDavid P Skoner
Dec 5, 2009·Allergy·J HellgrenL O Cardell
Mar 24, 2010·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Michael SchatzMark Kosinski
Sep 8, 2010·The Journal of Allergy and Clinical Immunology·Philippe J BousquetJean Bousquet
Nov 22, 2012·The Laryngoscope·Ahmad R SedaghatDavid A Kieff
Nov 28, 2012·International Archives of Allergy and Immunology·Philippe Jean BousquetJean Bousquet
Apr 1, 2014·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Michael S BlaissFelicia Allen-Ramey
Nov 20, 2015·Clinical and Translational Allergy·David PriceJean Bousquet
Jul 19, 2017·American Journal of Rhinology & Allergy·Lloyd P HoehleAhmad R Sedaghat

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Citations

Nov 7, 2019·American Journal of Rhinology & Allergy·Qasim HusainAhmad R Sedaghat

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