PMID: 9174860Jan 1, 1997Paper

Treatment of a giant haemangioma of the liver with Kasabach-Merritt syndrome by orthotopic liver transplant a case report

HPB Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery
J H LongevilleR T Padbury

Abstract

We describe a case of giant cavernous haemangioma of the liver with disseminated intravascular coagulopathy (Kasabach-Merritt syndrome) which was cured by orthotopic liver transplant. A 47 year old man presented with bleeding and tender massive hepatomegaly after tooth extraction. Investigations showed disseminated intravascular coagulopathy and a giant hepatic haemangioma involving both lobes of the liver. Initial treatment failed to resolve the coagulopathy and liver resection was attempted. At laparotomy the tumour was unresectable and the only option for cure was to offer a liver transplantation. The orthotopic liver transplant was performed 20 days after initial laparotomy. Subsequently, all coagulation parameters returned to normal and the patient remains well after 12 months. Orthotopic liver transplant can be considered for giant hepatic haemangioma with Kasabach-Merritt syndrome when resection is necessary and a partial hepatectomy is not technically feasible.

Citations

Jun 16, 2010·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Parsia A VagefiNathan M Bass
Aug 1, 2002·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Yuji KumashiroKoichi Tanaka
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Jul 6, 2010·Pediatric Transplantation·Disha SoodArvinder Singh Soin
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May 13, 2014·Pediatric Transplantation·Masahiro HatanakaMureo Kasahara
Apr 10, 2021·BMC Surgery·Qing-Song XieFu-Bao Liu
Feb 24, 2001·Clinics in Liver Disease·J F Trotter, G T Everson
Mar 19, 2019·Transplantation Proceedings·A ProdromidouG C Sotiropoulos

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