Treatment of acute Achilles tendon rupture - a multicentre, non-inferiority analysis.

BMC Musculoskeletal Disorders
Olof WestinP W Ackermann

Abstract

While numerous clinical studies have compared the surgical and non-surgical treatment of acute Achilles tendon rupture (ATR), there are no studies that have performed a non-inferiority analysis between treatments. Data from patients who were included in five randomised controlled trials from two different centres in Sweden were used. Outcomes at 1 year after ATR consisted of the patient-reported Achilles tendon Total Rupture Score (ATRS) and the functional heel-rise tests reported as the limb symmetry index (LSI). The non-inferiority statistical 10% margin was calculated as a reflection of a clinically acceptable disadvantage in ATRS and heel-rise outcome when comparing treatments. A total of 422 patients (350 males and 72 females) aged between 18 and 71 years, with a mean age of 40.6 (standard deviation 8.6), were included. A total of 363 (86%) patients were treated surgically. The ATRS (difference (Δ) = - 0.253 [95% confidence interval (CI); - 5.673;5.785] p = 0.36) and LSI of heel-rise height (difference = 1.43 [95% CI; - 2.43;5.59] p = 0.81), total work (difference = 0.686 [95% CI; - 4.520;6.253] p = 0.67), concentric power (difference = 2.93 [95% CI; - 6.38;11.90] p = 0.063) and repetitions (difference = - 1.30 [95% CI; - ...Continue Reading

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Citations

Aug 5, 2020·Journal of Experimental Orthopaedics·Niklas NilssonOlof Westin
Jan 21, 2021·Journal of Functional Morphology and Kinesiology·Domiziano TarantinoBruno Corrado
Feb 18, 2021·BMC Musculoskeletal Disorders·Olof WestinPaul Ackermann

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