Treatment of acute kidney injury in children: from conservative management to renal replacement therapy

Nature Clinical Practice. Nephrology
Timothy E Bunchman

Abstract

Over the past two decades, the etiology and therapy of acute kidney injury (AKI) in children has changed. Historically, hemolytic uremic syndrome was the major cause of pediatric AKI, but advances in technology have meant that sepsis and deterioration of often unrecognized long-term organ dysfunction are now more common causes of pediatric AKI in the developed world. At the same time, major advances in renal replacement therapy in children have occurred as a result of improved strategies for vascular access, more-adaptable equipment, and better techniques and protocols. This Review outlines the etiology, incidence, diagnosis, and treatment--both dialytic and non-dialytic--of pediatric AKI.

References

Oct 1, 1996·Advances in Renal Replacement Therapy·R S Parekh, T E Bunchman
Dec 31, 1997·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·N J MaxvoldT E Bunchman
Nov 30, 2000·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·B A Warady, T Bunchman
Jun 5, 2001·Pediatrics·S L GoldsteinR Sachdeva
Aug 16, 2001·Critical Care Medicine·J A Kellum, J M Decker
Jan 17, 2002·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·T E BunchmanP D Brophy
Apr 17, 2002·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Timothy E BunchmanMark R Benfield
May 1, 2002·Current Opinion in Pediatrics·Sharon Phillips Andreoli
Jul 18, 2002·Intensive Care Medicine·P E Marik
Oct 8, 2003·Critical Care Medicine·David Di GiantomassoRinaldo Bellomo
May 25, 2004·Journal of Intensive Care Medicine·Julie MarshallJoseph D Tobias
Aug 11, 2004·Chest·Jacques AlbanèseClaude Martin
Nov 2, 2004·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Robert S GillespieJordan M Symons
Jan 28, 2005·Kidney International·Stuart L GoldsteinJames D Fortenberry
Feb 8, 2005·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Shirley Hui-StickleStuart L Goldstein
Apr 6, 2005·Annals of Internal Medicine·Jan O FriedrichJoseph Beyene
Jun 11, 2005·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Ifeoma C Anochie, Felicia U Eke
Dec 24, 2005·Kidney International·D J AskenaziS L Goldstein
Mar 31, 2006·Kidney International·A LauschkeK-U Eckardt
Mar 31, 2007·Kidney International·A Akcan-ArikanS L Goldstein
Apr 10, 2007·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Christine M Hardy FramsonJohanna T Dwyer
Apr 28, 2007·Contributions to Nephrology·John A KellumClaudio Ronco
Apr 28, 2007·Contributions to Nephrology·Prasad Devarajan
Aug 1, 2007·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Arvind BaggaUNKNOWN Acute Kidney Injury Network
Aug 7, 2007·Critical Care : the Official Journal of the Critical Care Forum·Michael ZappitelliStuart L Goldstein
Oct 4, 2007·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Kimberly K WashburnStuart L Goldstein
Dec 7, 2007·Seminars in Nephrology·Prasad Devarajan
Jan 30, 2008·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Francisco X FloresStuart L Goldstein
May 23, 2008·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Brady S MoffettJohn Lynn Jefferies

❮ Previous
Next ❯

Citations

Nov 26, 2009·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·David J HobbsTimothy E Bunchman
Oct 21, 2011·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Rajit K BasuStuart L Goldstein
Feb 13, 2013·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Adam RomanovskySean M Bagshaw
Feb 19, 2011·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Aicha MerouaniPhilippe Jouvet
Mar 30, 2013·Critical Care Clinics·Rodney C Daniels, Timothy E Bunchman
Nov 9, 2010·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Rajit K BasuDerek S Wheeler
Jul 20, 2017·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Rajiv SinhaRupesh Raina

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.